11.07.2015 Views

Pulmonary Hypertension: Beyond the Swan Ganz Catheter

Pulmonary Hypertension: Beyond the Swan Ganz Catheter

Pulmonary Hypertension: Beyond the Swan Ganz Catheter

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Atrial Septostomy• Done only for refractory patients who need urgent correction of cardiac symptoms• Balloon dilation of atrial septum• Creates R‐> L cardiac shunt• RV decompressed + LV filling improved = better CO– Law et al. (2007).• Forty‐six atrial septostomies on 43 patients. 0.3 to 30 years. Primary PHTN, PHTNassociated with repaired congenital heart defects, and secondary causes of PHTN.• Mean baseline pulmonary vascular resistance was 35 +/‐ 17 Wood units, and meanpulmonary artery pressure was 74 +/‐ 19 mm Hg.• Patients surviving > or = 30 days had immediate improvement in cardiac index (from 2.3to 2.9 L x min(‐1) x m(‐2), P < .0001), right atrial pressure (RAp) (from 9.9 to 8.3 mm Hg, P< .05), and oxygen delivery (from 424 to 491 mL O2 per minute, P< .01), with a decreasein systemic oxygen saturation (from 93% to 86%, P < .001).• <strong>Pulmonary</strong> artery pressure was unchanged (P = .3). New York Heart Association class andsymptoms of syncope improved (P < .01).• Event‐free survival at 1, 2, and 3 years was 84%, 77%, and 69%, respectively.• 22% 30 day mortality. Associated with preceding decompensations in <strong>the</strong> intensive careunit (P < .001) and a higher RAP (P < .001).American Heart Journal, 153(5), pp. 779‐784

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