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Pulmonary Hypertension: Beyond the Swan Ganz Catheter

Pulmonary Hypertension: Beyond the Swan Ganz Catheter

Pulmonary Hypertension: Beyond the Swan Ganz Catheter

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More Hope…• Perhaps <strong>the</strong> inhibiting <strong>the</strong> serotonin transmitters and receptors will help…• Guignabert et al. (2005). Serotonin transporter inhibition prevents andreverses monocrotaline‐induced pulmonary hypertension in rats.Circulation, 111, pp. 2812–2819.• Hironaka et al. (2003). Serotonin receptor antagonist inhibitsmonocrotaline‐induced pulmonary hypertension and prolongs survival inrats. Cardiovascular Research, 60, pp. 692–699.• Keegan et al. (2001). Contribution of <strong>the</strong> 5‐HT1B receptor to hypoxiainducedpulmonary hypertension –converging evidence using 5‐HT1Breceptorknockout mice and <strong>the</strong> 5‐HT1B/1D‐receptor antagonistGR127935. Circulation Research, 89, pp. 1231–9.• Marcos et al. (2003). Serotonin transporter inhibitors protect againsthypoxic pulmonary hypertension. American Journal of Respiratory andCritical Care Medicine, 168, pp. 487–93.

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