2013-2014 Course Selection Book - SUNY Upstate Medical University

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AUTONOMIC PHARMACOLOGY. . . . . . . . . . . . . . . . . . . . . PHA6191 Credit HourCoordinator(s):Dr. WojcikiewiczPrerequisite(s):First year core curriculumPeriod Offered:FallCourse Description: This course covers the essentialfeatures of the autonomic nervous system inhumans, and agents that modify this system,including therapeutic and recreational drugs andtoxic agents. The course will be composed of acombination of graduate student-specific lecturesand tutorials together with selected lectures fromthe Medical School Pharmacology course (540PHA).Textbook(s): Goodman and Gilman’s, ThePharmacological Basis of TherapeuticsPRINCIPLES AND PRACTICES OF DRUGDISCOVERY AND DEVELOPMENT. . . . . . . . . . . . . . . . . . . . . PHA622Total Credit: 1 (2 Hr sessions/every other week)Coordinator(s):Hong LuJuntao LuoInstructor(s): Hong Lu, Juntao Luo, Ziwei Huang,Debasdhis Ghosh, Jing An, and Golam MohiPrerequisite(s): Undergraduate (senior level) biologyand chemistry, or permission of the Instructor.Period Offered:Fall SemesterCourse Description: In the U.S. and aroundthe world, there is increasing effort by theNIH and other federal and private fundingagencies to promote the translation of novellaboratory research discoveries into medical andcommercial applications and demand from thebiopharmaceutical industry for new therapeutictechnologies and products from the academiadue to the downsizing and outsourcing of drugdiscovery and development programs in largepharmaceutical companies. Additionally, anincreasing portion of graduate students in thepharmacology program will end with working inpharmaceutical industries. Thus, it is importantfor pharmacology students to understand theprinciples and practices of drug discovery anddevelopment, for both current thesis work andfuture career development. This new course willbe a 1-credit elective course for pharmaologystudents and any graduate student who isinterested in drug discovery and development.It will cover the key principles and practices ofdrug discovery and development. Topics willinclude introduction and overview of academicdrug discovery and development at Upstate,structure-based drug design, combinatorialchemistry and high throughput screening in drugdiscovery, in vitro drug screening - identificationand optimization of lead compound, mousemodels for drug development, early safety andefficacy assessments, pharmacokinetics/toxicology(PK/TOX) studies in drug development, andnanotechnology in drug delivery.Course Objectives: Students will havecomprehensive understanding of the generalprinciples and practices in drug discovery anddevelopment. through this course, faculty from theDepartment of Pharmacology will deliver lecturesto provide students with an understanding of theprocess of drug development from the identificationof novel targets to the structural-based drugdesign, from the combinatorial chemistry andhigh-throughput drug screening for hit compoundidentification and lead optimization; from themolecular and cellular assays to the in vivo animalmodels for drug evaluation; from the PK/TOXstudy to drug molecules in the preclinical studies.Students will be expected to think critically aboutthe objectives and experimental designs of thevarious stages of drug development. Students willbe required to read literatures on each topic andwrite assays to summarize the development andperspectives on each stage of drug development.PHARMACOLOGY SEMINAR0 Credit HoursPHA645Coordinator(s):Dr. Y. HuangPharmacology FacultyPrerequisite(s):NonePeriod Offered:Fall/SpringCourse Description: Graduate students and facultywill meet every week during the academic yearto participate in seminars. Seminars will be givenby outside speakers and Departmental members,including Graduate Students who, after their firstyear, will be required to give one presentation peryear. Grades will be assigned based on performance.Thurs., 12:00 - 1:00 PM Room 3105 Weiskotten HallTextbook(s):None29
PHARMACOLOGY LABORATORYROTATIONSPHA653Variable CreditCoordinator(s):Dr. Y. HuangPharmacology FacultyPrerequisite(s): Course is limited to studentsstudying for a degree in Pharmacology, or byspecial arrangement.Period Offered: Fall/Spring by arrrangementCourse Description: Students learn methods ofresearch used by the Pharmacology Faculty. Problemdesign, research methods and the preparation of awritten report are emphasized.This course is not offered for thesis or dissertationresearch, which is course 700PHA.Textbook(s):NoneRESEARCH IN PHARMACOLOGY. . . . . . . . . . . . . . . . . . . . . PHA700Variable CreditCoordinator(s):Dr. Y. HuangPharmacology FacultyPrerequisite(s): Approval of the departmentPeriod Offered:Fall/SpringCourse Description: Original dissertation researchin Pharmacology under the supervision of aPharmacology Faculty member and monitored byan advisory committee.Textbook(s):NonePhysiology ProgramCELL PHYSIOLOGY OF EXCITABLE CELLS(SAME AS N602 & PHA602) PHY6022 Credit HoursCoordinator(s): Dr. Richard Veenstra, Director(Pharmacology)Prerequisite(s): Foundations of Biolmedical SciencesCore CurriculumPeriod Offered:Spring March-JuneMust have 3 or more graduatestudents registered to offer courseCourse Description: This course will present anddiscuss key concepts of ion vhannel function andhow they relate to the cell physiology of excitablecells. The Instructor(s) will present Discussiontopics on Reviews of Electricity and Action30Potentials, the Hodgkin-Huxley model for thenerve action potential, theories for electrodiffusionand ion permeation, and visual transduction. Theremainder of the course will be primarily studentled discussions of selected chapters from the CellPhysiology Sourcebook covering concepts ofIon Channel Structure, Function, Regulation, andChannelopaties (human diseases caused by ionchannel dysfunction), with the guidance of theInstructors. There will be approximately 14 to 16student led discussions (3-5 per student) and 6-7lectures presented by the Instructors. Grades arebased on student attendance, presentation, andparticipation in the in-class discussions. Thereis no course examination, although take-homeproblems may be assigned to increase studentparticipation. A minimum of 3 matriculatedgraduate students must register for this course tobe offered.Textbook(s): N. Sperelakis, Cell PhysiologySourcebook: Essentials of Membrane Biophysics, 4 thEdition, 2012BIOMATERIALS AND MEDICAL DEVICES(SU COURSE BEN468/668) PHY6032 Credit HoursCoordinator(s):Dr. Barry KnoxInstructor(s):Physiology FacultyPeriod Offered:SpringCourse Description: This course is designed tobe an introduction to the field of biomaterials andmedical devices. The basic material science ofmetals, ceramics, polymers, and biological materialsused in medical applications will be presented.Major concepts will focus on structure-propertyrelationships and the physical and mechanicalproperties of these important classes of materials.Textbook(s): None - selected readings will beassigned.
Page 1 and 2: 2013-2014 COURSESCollege of Graduat
Page 3 and 4: Contemporary Cellular, Molecular an
Page 6: Academic Calendar1
Page 9 and 10: Registration InformationFALL SEMEST
Page 11 and 12: Registration InstructionsSUNY Gradu
Page 14: CORECURRICULUMCore CurriculumPh.D.
Page 17 and 18: RESPONSIBLE CONDUCT OF SCIENTIFICRE
Page 19 and 20: 14Biochemistry And MolecularBiology
Page 21 and 22: SCIENTIFIC WRITING IN BIOCHEMISTRY.
Page 23 and 24: Cell and DevelopmentalBiologyGROSS
Page 26 and 27: Recognition by the T-Cell Receptor;
Page 28 and 29: NeuroscienceINTRODUCTION TO NEUROSC
Page 30 and 31: ADVANCED TOPICS IN RECEPTORS ANDCEL
Page 32 and 33: Period Offered: Offered year round
Page 36 and 37: METHODS OF PHYSIOLOGY RESEARCH. . .
Page 38 and 39: performance on the assignments, and
Page 40: FORMS ANDREQUIREMENTS
Page 44 and 45: DEPARTMENT OF CELL AND DEVELOPMENTA
Page 46: DEPARTMENT OF BIOCHEMISTRY AND MOLE
Page 50 and 51: DEPARTMENT OF MICROBIOLOGY AND IMMU
Page 52: DEPARTMENT OF MICROBIOLOGY AND IMMU
Page 55 and 56: 5. Dissertation Defense Committee:
Page 57 and 58: Spring II N507 Medical Neuroscience
Page 60: PHYSIOLOGY PROGRAMPh.D. and M.S. Re

2013-2014 Course Selection Book - SUNY Upstate Medical University

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