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Gaylord Palms Resort and Convention Center | March 27–31, <strong>2011</strong> | Orlando, Florida, USA<br />
3:30 – 4:00 pm Page 41<br />
4:00 – 4:30 pm Page 41<br />
1:30 – 4:30 pm Osceola B<br />
1:30 – 2:00 pm Page 43<br />
2:00 – 2:30 pm Page 43<br />
3:00 – 3:30 pm Page 43<br />
3:30 – 4:00 pm Page 44<br />
4:00 - 4:30 pm Page 44<br />
Tuesday, March 29<br />
9:00 am – 12:00 pm Osceola A<br />
9:00 – 9:30 am Page 46<br />
9:30 – 10:00 am Page 46<br />
10:30 – 11:00 am Page 46<br />
11:00 – 11:30 am Page 47<br />
11:30 am – 12:00 pm Page 47<br />
Challenges and Successes of Translational Research in the Public Domain:<br />
Retrospective and Prospective Analyses and Case His<strong>to</strong>ries of “Probes <strong>to</strong><br />
Leads” From Six Years of the Molecular Libraries Program; Thomas “T.C.”<br />
Chung, Conrad Prebys Center for Chemical Genomics at Sanford-Burnham<br />
Medical Research Institute<br />
Translation in Action: MRCT's Centre for Therapeutics Discovery;<br />
Justin Bryans, MRC Technology<br />
Track III » Session 1: Target Resuscitation:<br />
Drug Repositioning Opportunities<br />
Session Chair: Roger Bosse, PerkinElmer<br />
Plenary: Drug Repositioning: How it Fits With Current Drug-Discovery<br />
Trends; Chris<strong>to</strong>pher A. Lipinski, Melior Discovery<br />
Prodrugs: Regula<strong>to</strong>ry and Clinical Development Requirements For Approval;<br />
Ken Phelps, Camargo Pharmaceutical Services, LLC<br />
Exploring Ligand-Directed Functional Selectivity of GPCR With Bret-Based<br />
Biosensor Arrays and Label-Free Impedance Measurements; Linking<br />
Signaling Signature <strong>to</strong> Drug Efficacy; Michel Bouvier, Drug Discovery Group,<br />
University of Montreal<br />
A Rapid Assay for Identifying New Drug Candidates From Approved<br />
Drugs for Repositioning <strong>to</strong> Treat Giardiasis; Catherine Chen, NIH Chemical<br />
Genomics Center<br />
HTS for REST Inhibi<strong>to</strong>rs in Neural Progenies of Human ES Cells;<br />
Anselme Perrier, I-Stem<br />
Track I » Session 2: Innovations in Screening Biology:<br />
Assays, Techniques and Instrumentation<br />
Session Chair: Jonathan O’Connell, Bris<strong>to</strong>l-Myers Squibb Company<br />
Plenary: The Evolution of HTS at Bris<strong>to</strong>l-Myers Squibb: Enabling<br />
the Support of the Most Relevant Bio-Assays; Jonathan O’Connell,<br />
Bris<strong>to</strong>l-Myers Squibb Company<br />
Etv6-NTRK3, A Constitutively Active Tyrosine Kinase Found in Variety<br />
of Tumors, is Unique in its Mechanism of Transformation;<br />
Jack Allen, Merrimack Pharmaceuticals<br />
High-Throughput Screening With Real-Time PCR: Reducing it <strong>to</strong> Practice;<br />
Andrea Wes<strong>to</strong>n, Bris<strong>to</strong>l-Myers Squibb Company<br />
New Ion Channel Screening Technologies Enabling Development of High<br />
Quality and High-Throughput Assays in a Plate-Based Screening Group;<br />
Juha Kammonen, Pfizer<br />
Creating a Holistic Screening Strategy for Label-Free Technology in a Plate<br />
Based Screening Group; Rachel Russell, Pfizer Global Research & Development<br />
<strong>SLAS</strong>.org/events/sbs11 | 31