MCDB 165A - BIOLOGY OF THE CELL SYLLABUS – FALL ... - UCLA

Mid-term and final exams will consist of a mix of multiple choice questions and shortanswers. They will cover materials from the lectures, readings, and discussion sessions. Thefinal exam will be cumulative. Exams must be written in ink, no pencil allowed.Makeup exams are NOT given. In the case that you are unable to take an examination orhave an illness or emergency, you are responsible for contacting your TA before the examination.A written verification regarding the illness or emergency must be provided. If you feel that amistake in grading has been made on your exam, submit your exam and a typed explanation toyour teaching assistant by Friday (5pm) of the week following the exam. When you submit yourexam for re-grading, the entire content of the exam will be taken into consideration.Written Assignment / EssayA 4-page essay (double-spaced) on a subject related to one of the papers of the discussionsessions. Due November 25th. or earlierFinal ExamThursday, December 11 th- 3-6pmPapers for Discussion Sessions:Paper 1:Nydegger S, Khurana S, Krementsov DN, Foti M, Thali M. Mapping of tetraspanin-enrichedmicrodomains that can function as gateways for HIV-1. J Cell Biol. 2006 Jun 5;173(5):795-807Paper 2:Kakinuma N, Roy BC, Zhu Y, Wang Y, Kiyama R. Kank regulates RhoA-dependent formation of actinstress fibers and cell migration via 14-3-3 in PI3K-Akt signaling. J Cell Biol. 2008 May 5;181(3):537-49.Paper 3:Lampugnani MG, Orsenigo F, Gagliani MC, Tacchetti C, Dejana E. Vascular endothelial cadherin controlsVEGFR-2 internalization and signaling from intracellular compartments. J Cell Biol. 2006 Aug14;174(4):593-604.Paper 4:Pegtel DM, Ellenbroek SI, Mertens AE, van der Kammen RA, de Rooij J, Collard JG. The Par-Tiam1complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity. Curr Biol.2007 Oct 9;17(19):1623-34.Paper 5:Bonnon C, Bel C, Goutebroze L, Maigret B, Girault JA, Faivre-Sarrailh C. PGY repeats and N-glycansgovern the trafficking of paranodin and its selective association with contactin and neurofascin-155.Mol Biol Cell. 2007 Jan;18(1):229-41Paper 6:Bethani I, Lang T, Geumann U, Sieber JJ, Jahn R, Rizzoli SO. The specificity of SNARE pairing inbiological membranes is mediated by both proof-reading and spatial segregation. EMBO J. 2007 Sep5;26(17):3981-92