hemosyl-250mg tablet - Lomus Pharmaceuticals Pvt. Ltd.
hemosyl-250mg tablet - Lomus Pharmaceuticals Pvt. Ltd.
hemosyl-250mg tablet - Lomus Pharmaceuticals Pvt. Ltd.
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HEMOSYL TabletDosage Forms/CompositionTablet: Each <strong>tablet</strong> contains Ethamsylate 250 mg/500mg.Pharmacological IndexAntihaemorrhagicINDICATIONPre-, per-, or post surgical capillary hemorrhages.Capillary haemorrhages: haematuria, haematemesis, melaena, epistaxis,gingivorrhagia.Metrorrhagia, primary or IUD-related menorrhagia in the absence of organicpathology.Periventricular hemorrhages in premature babies.ContraindicationsHypersensitivity, porphyria, pregnancy and lactation.Adverse ReactionsNausea, headache, skin rash. In most cases, these symptoms disappear spontaneously.Drug InteractionsIncreased toxicity: MAO inhibitors hallucinationsMechanism of ActionA potent antihistamine and serotonin antagonist, competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, andrespiratory tractPharmacodynamics/KineticsMetabolism: Almost completelyElimination: >50% excreted in urine (primarily as metabolites); ~25% excreted infecesUsual DosageAdultsPre surgical: 1 or 2 <strong>tablet</strong>s (250-500 mg)Post surgical: 1 or 2 <strong>tablet</strong>s (250-500 mg) i.m. every 4 - 6 hours as long as the risk ofbleeding persists.Internal medicine: generally 1 or 2 <strong>tablet</strong>s 2 - 3 times a day (1000 - 1500 mg) to betaken with meals with a little water.Gynaecology, meno-metrorrhagia: 1 or 2 <strong>tablet</strong>s 3 times a day (1500 mg) to be takenwith meals with a little water. Treatment lasts 10 days and starts 5 days before theexpected onset of menses.
ChildrenHalf the adult dose of 250 mg <strong>tablet</strong>.Because of its high concentration of active principle, Hemosyl 500 is not appropriatefor children.LOMUS Drug Information Center<strong>Lomus</strong> <strong>Pharmaceuticals</strong> <strong>Pvt</strong>. <strong>Ltd</strong>.P.O. Box No 4506, <strong>Lomus</strong> House (Corporate office),Kailash Chour, Lazimpat, Kathmandu, NepalPh: 4436396 (Hunting Line). Fx: 977-1-4436395E-mail: druginfo@lomus.com.np