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Computerized Training of Working Memory in Children with ADHD ...

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WM and distractability (I)WM and distractability (II)Ability to attend to only part<strong>of</strong> a noisy environment.Fails <strong>in</strong> approx 33% <strong>in</strong>dividuals…Those <strong>with</strong> low work<strong>in</strong>g memory capacity(Conway, Cowan, Bunt<strong>in</strong>g, 2001)(Kane et al., Psychol Sci, 18(7): 614-621, 2007)Impairments <strong>in</strong> cl<strong>in</strong>icalpopulations• Concurrents <strong>with</strong> disorders <strong>of</strong>– Prefrontal or parietal cortex– Dopam<strong>in</strong>e system• Populations– Traumatic head <strong>in</strong>jury–Stroke– <strong>ADHD</strong>– Schizophrenia–MSExperienced as•Less focused•More distractible•Problems <strong>in</strong> plann<strong>in</strong>g•”Forgett<strong>in</strong>g”<strong>ADHD</strong>• Proposed endophenotypes–Rewardcircle– Temporal process<strong>in</strong>g– Inhibitory function– <strong>Work<strong>in</strong>g</strong> memory– Barkley, R (1997)– Rapport, MD (2000)– Castellanos, FX and Tannock, R (2002)WM and <strong>ADHD</strong>WM and <strong>ADHD</strong>Span-board like tasksDowson -04CANTAB WM1.15WAIS span-board-Kempton -991.331.22Barnett -011.451.0646 studies on WM <strong>in</strong> <strong>ADHD</strong>Review by Mart<strong>in</strong>ussen et al. 2005Westerberg -04-1.34Mean = 1.26 SD3

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