Ca - LISM
Ca - LISM
Ca - LISM
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<strong>Ca</strong>lcium accumulation (nmoles/mg protein)Accumulation of calcium by reconstituted<strong>Ca</strong>-ATPase in sealed vesicles5000400030002000100000 500 1000Time (secs)PC + 10%cardiolipinPC + 10% PAPC<strong>Ca</strong>ATPhydrolysisxleak