11.07.2015 Views

Greg Calligaro Definition and classification of pulmonary hypertension

Greg Calligaro Definition and classification of pulmonary hypertension

Greg Calligaro Definition and classification of pulmonary hypertension

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PAH related to portal <strong>hypertension</strong>• Prevalence <strong>of</strong> 2-5% by RHC: up to 17% in livertransplant c<strong>and</strong>idates• Related to degree <strong>of</strong> porto-systemic shunting, notunderlying hepatocellular dysfunction• Worse mortality than IPAH alone• Liver transplant may improve survival (if mild tomoderate PH) - (28-56% 5 year survival)Budhiraja R et al. Chest. 2003.Kawut SM et al. Liver Transpl. 2005.Krowka MJ et al. Clin Chest Med. 2005.

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