Greg Calligaro Definition and classification of pulmonary hypertension
Greg Calligaro Definition and classification of pulmonary hypertension
Greg Calligaro Definition and classification of pulmonary hypertension
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WHO Group 1 PAH1. PAH•Idiopathic PAH•Heritable•Drug- <strong>and</strong> toxin-induced•Associated with:−CTD−HIV infection−portal <strong>hypertension</strong>−CHD−schistosomiasis−chronic hemolytic anemia• Persistent PH <strong>of</strong> newborn• Consists <strong>of</strong> IPAH, heritablePAH (BMPR2 <strong>and</strong> ALK1genes)• Drugs <strong>and</strong> toxin-inducedPAH:– Definite: aminorex,fenfluramine, toxic rapeseedoil– Likely: amphetamines, L-tryptophan, cocaine, St.John’s Wort, SSRI’sSimonneau G et al. J Am Coll Cardiol. 2009;54;S43-S54.
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