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Conformation Sensitive Capillary Electrophoresis Conformation ...

Conformation Sensitive Capillary Electrophoresis Conformation ...

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Validation•Testing the Sanger protocol using the GMD controls gives asensitivity of 98% (47/48); the only mutation not detected was80.1G>A•Two main factors affecting detection capability are the GC contentof the fragment and the position of the mutation in the fragment

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