endotoxins adsorption - CRRT Online

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Plasmapheresis vs Plasma Exchange• Plasma Exchange(PE) centrifugation membrane• Plasmapheresis (PP) orPlasmafiltration (PF)PLASMA FILTERPLASMA FILTERPlasmaPlasmaFFP/colloid/IgGPatientHonore PM et al.Ann Intensive Care 2011PatientADSORBANTCOLUMN
Hybrid Systems : PMX Cartridges(EUPHAS)64 Post-Surgical SepsisRandomizationPMX Treatment for 2 Sess (N=34)Standard Therapy (N=30)34 PMX Treatment 30 Standard TherapySOFA Score Improved No Changes(P)Hemodynamics(MAP) Improved No Improvement(P)28 Days Mortality 32 % 55 % (P 0.43)Vasopressors Decreased No Changes(T)22) Cruz D et al JAMA 2009; 301:2445-2452
Page 1: Exp Studies for HVHF,HPHF&Hybrid Th
Page 5 and 6: III) Should We Target SIRS,Immunopa
Page 9 and 10: Solute Classes by MolecularWeightDa
Page 11 and 12: Recent HPHF Studies in Sepsis:mL /
Page 13 and 14: VI)Hybrid Systems Recent HPHF Studi
Page 15: Hybrid Systems : The Possible Answe
Page 19 and 20: AN69 ST* and Heparin AdsorptionHep.
Page 21 and 22: -New HyperAdsorptive Membrane(oXiri
Page 23 and 24: oXiris: Action ModeLow molecular we
Page 25 and 26: Endotoxins adsorption - in vitroHon
Page 27 and 28: Β2M Adsorption IsothermsPorous AN6
Page 29 and 30: LAL response EU/mLEndotoxin Removal
Page 31 and 32: RIFLE CriteriaGFR CriteriaUrine Out
Page 33 and 34: VIII) The Future: Ongoing PRT’s:
Page 35 and 36: =75Patients (%)Patients (%)DoReMi D

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