endotoxins adsorption - CRRT Online

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IVOIRE STUDY140patients with Septic Shock and Acute KidneyInjury35ml/kg/hRandomizationwithin 24 hours ofICU admission(! Early septicshock)70ml/kg/hAny dose ofvasopressors(Noradrenaline)Or > 5µg/kg/m ofDopamine- Oliguria < 0.5ml/kg/h- creatinine X 2MortalityRIFLE InjuryD28D9030
RIFLE CriteriaGFR CriteriaUrine Output CriteriaRiskInjuryIncreased creatininex1.5 or GFR decrease> 25%Increased creatinine x2or GFR decrease > 50%UO < .5ml/kg/hx 6 hrUO < .5ml/kg/hx 12 hrHighSensitivityFailureLossESKDIncrease creatininex3or GFR decrease> 75%UO < .3ml/kg/hx 24 hr orAnuria x 12 hrsPersistent ARF** = complete loss ofkidney function > 4 weeksEnd Stage Kidney Disease(> 3 months)HighSpecificity
Page 1: Exp Studies for HVHF,HPHF&Hybrid Th
Page 5 and 6: III) Should We Target SIRS,Immunopa
Page 9 and 10: Solute Classes by MolecularWeightDa
Page 11 and 12: Recent HPHF Studies in Sepsis:mL /
Page 13 and 14: VI)Hybrid Systems Recent HPHF Studi
Page 15 and 16: Hybrid Systems : The Possible Answe
Page 17 and 18: Hybrid Systems : PMX Cartridges(EUP
Page 19 and 20: AN69 ST* and Heparin AdsorptionHep.
Page 21 and 22: -New HyperAdsorptive Membrane(oXiri
Page 23 and 24: oXiris: Action ModeLow molecular we
Page 25 and 26: Endotoxins adsorption - in vitroHon
Page 27 and 28: Β2M Adsorption IsothermsPorous AN6
Page 29: LAL response EU/mLEndotoxin Removal
Page 33 and 34: VIII) The Future: Ongoing PRT’s:
Page 35 and 36: =75Patients (%)Patients (%)DoReMi D

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