Abstract book - Prof. Per Jensen, Ph.D. - Bergische Universität ...

204 Poster session, J41Tissue Bonding Ability of Borate Analogue to Hench's BioglassContaining Antibacterial AgentA.M. Hezma 1 , A.M. Abdelghany 21 Spectroscopy Department, National Research Center, 12311, Dokki, Cairo, Egyptahezma@yahoo.com2 Spectroscopy Department, National Research Center, 12311, Dokki, Cairo, Egypta.m_abdelghany@yahoo.comHezma A.M.Abdelghany A.M.Bioactive borate glasses with and without low level doping of (AgO) antibacterialagent in the nano scale were produced by fully replacement of SiO 2 with B 2 O 3 inthe well known Hench's bioglass (45S5) to obtain a new class of scaffold material.Controllable corrosion rates and conversion of prepared glasses to HA by solutionprecipitation reaction in aqueous dilute phosphate solution at 37°C were examinedusing X-ray diffraction to identify the crystalline phases that precipitated withinthese samples during the treatment. Fourier transform spectroscopy was used tojustify the function of hydroxyapatite as an indication of the bioactivity potential ofthe studied glasses after immersion in aqueous phosphate solution. The results areinterpreted on the basis of current views on the corrosion mechanism of suchglasses in relation to their composition and constitution.Furthermore, antimicrobial activity of the prepared glasses were studied againstGram-negative bacteria: Escherichia coli, Gram-positive Bacillus cereus, Bacillussubtilis using minimum inhibitory zone (MIZ) method.