ConclusionsWhen a sufficient number <strong>of</strong> treatments were performed, the iPulse constant spectrum <strong>IPL</strong> was found to be effective <strong>in</strong> thisprelim<strong>in</strong>ary study <strong>in</strong> the treatment <strong>of</strong> benign pigmented lesions, acne and <strong>in</strong> the long-term delay <strong>of</strong> hair regrowth <strong>in</strong> hirsutism.Normal treatment related problems <strong>in</strong>clud<strong>in</strong>g patient assessed pa<strong>in</strong> response and side effects us<strong>in</strong>g the iPulse <strong>IPL</strong> with itsconstant spectral output, large 8.9 cm 2 spot size and relatively low fluence characteristics, were found to be comparable<strong>in</strong> dark <strong>Indian</strong> sk<strong>in</strong> to those reported <strong>in</strong> the literature <strong>in</strong> lighter sk<strong>in</strong> types with conventional <strong>IPL</strong> devices. Early <strong>in</strong>dications<strong>of</strong> efficacy <strong>in</strong> the treatment <strong>of</strong> hirsutism, pigmentation and acne were broadly similar to lasers and other <strong>IPL</strong> systems <strong>in</strong>lighter sk<strong>in</strong> types.Both the follow-up period and the number <strong>of</strong> lesions <strong>in</strong>cluded <strong>in</strong> the present study may not be sufficient to fully evaluatethe potentials <strong>of</strong> this treatment modality as well as the true <strong>in</strong>cidence <strong>of</strong> recurrence <strong>of</strong> the orig<strong>in</strong>al condition. Therefore, theresults obta<strong>in</strong>ed should be confirmed <strong>in</strong> larger studies.10
References1. Alster TS. Complete elim<strong>in</strong>ation <strong>of</strong> large café-au-lait birthmarks by the510-nm pulsed dye laser. Plast Reconstr Surg 1995; 95: 1660–4.2. Trelles MA, Verkruysse W, Picker<strong>in</strong>g JW, et al. Monol<strong>in</strong>e argon laser(512 nm) treatment <strong>of</strong> benign pigmented lesions with long pulse length.J Photochem Photobiol 1992; 16:357–65.3. Alster TS, Williams CM. Cafe-au-lait macule <strong>in</strong> type V sk<strong>in</strong>: successfultreatment with a 510 nm pulsed dye laser. J Am Acad Dermatol 1995;33: 1042–3.4. Somyos K, Boonchu K, Somsak K, et al. Copper vapour laser treatment<strong>of</strong> cafe-au-lait macules. Br J Dermatol 1996; 135:964–8.5. Fitzpatrick RE, Goldman MP, Ruiz-Esparza J. Laser treatment <strong>of</strong> benignpigmented epidermal lesions us<strong>in</strong>g a 300 nsecond pulse and 510 nmwavelength. J Dermatol Surg Oncol 1993; 19:341–7.6. Chu A, Cunliffe WJ. <strong>Pulsed</strong>-dye laser treatment for <strong>in</strong>flammatory acnevulgaris: randomised controlled trial. Lancet. 2003; 362:1347-1352.7. Butterwick KJ, Butterwick LS, Han A. Laser and light therapies for acnerosacea. J Drugs Dermatol. 2006; 5(1):35-9.8. Gold MH, Bell MW, Foster TD, Street S. One-year follow-up us<strong>in</strong>g an<strong>in</strong>tense pulsed light source for long-term hair removal. J Cutan LaserTher. 1999 1(3):167-71.9. Omi T, Clement M. The use <strong>of</strong> a constant spectrum, uniform temporalpr<strong>of</strong>ile <strong>in</strong>tense pulsed light long-term hair removal <strong>in</strong> Asian sk<strong>in</strong>. JCosmetic Laser Ther. 2006; 8:138-145.10. Bedewi AF. Hair removal with <strong>in</strong>tense pulsed light. Lasers Med Sci.2004; 19(1):48-51.11. Bjerr<strong>in</strong>g P, Cramers M, Egekvist H, Christiansen K, Troilius A. Hairreduction us<strong>in</strong>g a new <strong>in</strong>tense pulsed light irradiator and a normal moderuby laser. J Cosmetic Laser Ther. 2006. 2(2):63-71.References16. Anderson RR, Margolis RJ, Watanabe S, et al. Selectivephotothermolysis <strong>of</strong> cutaneous pigmentation by Q-switched Nd:YAGlaser pulses at 1064 nm, 532 and 355 nm. J Invest Dermatol1989; 93:28-32.17. Kono T, Manste<strong>in</strong> D, Chan HH, Nozaki M, Anderson RR. Q-SwitchedRuby Versus Long-<strong>Pulsed</strong> Dye Laser Delivered With Compression forTreatment <strong>of</strong> Facial Lentig<strong>in</strong>es <strong>in</strong> Asians. Lasers Surg Med 2006; 38:94-97.18. Grevl<strong>in</strong>k JM, van Leeuwen RI, Anderson RR, et al. Cl<strong>in</strong>ical andhistological responses <strong>of</strong> congenital melanocytic nevi after a s<strong>in</strong>gletreatment with Q-switched lasers. Arch Dermatol 1997; 133:349-53.19. Goldberg DJ. Laser treatment <strong>of</strong> pigmented lesions. Dermatol Cl<strong>in</strong>1997; 15:397-407.20. Kopera D, Hohenleutner U, Landthaler M. Quality-switched ruby lasertreatment <strong>of</strong> solar lentigenes and Becker’s nevus: a histopathologicaland immunohistochemical study. Dermatology 1997; 194:338-43.21. Gold MH, Foster TD, Bell MW. Nevus spillus successfully treated withan <strong>in</strong>tense pulsed light source. Dermatol Surg. 1999; 25:254-5.22. Adatto MA. Photorejuvenation <strong>of</strong> the forearms by treat<strong>in</strong>ghyperpigmented lesions with <strong>in</strong>tense pulsed light source: a case report.J Cosmetic Laser Ther. 2003. 5(2):117-9.23. Kligman DE, Zhen Y. <strong>Intense</strong> pulsed light treatment <strong>of</strong> photoaged facialsk<strong>in</strong>. Dermatol Surg. 2004; 30(8):1085-90.24. Clement M, Daniel G, Trelles M. Optimis<strong>in</strong>g the design <strong>of</strong> a broad-bandlight source for the treatment <strong>of</strong> sk<strong>in</strong>. J Cosmetic Laser Ther. 2005;7:177-189.25. Alster TS. Laser Treatment <strong>of</strong> Darker Sk<strong>in</strong> Phototypes: Recent Progress.Cosmetic dermatol. 1999; Dec:13-16.12. Huang YL, Liao YL, Lee SH, Hong HS. <strong>Intense</strong> pulsed light for thetreatment <strong>of</strong> facial freckles <strong>in</strong> Asian sk<strong>in</strong>. Dermatol Surg. 2002;28(11):1007-12.13. Negishi K, Kushikata N, Tezuka Y, Takeuchi K, Miyamoto E, Wakamatsu S.Study <strong>of</strong> the <strong>in</strong>cidence and nature <strong>of</strong> "very subtle epidermal melasma" <strong>in</strong>relation to <strong>in</strong>tense pulsed light treatment. Dermatol Surg. 2004; 30(6):881-6.14. Wang CC, Hui CY, Sue YM, Wong WR, Hong HS. <strong>Intense</strong> pulsed lightfor the treatment <strong>of</strong> refractory melasma <strong>in</strong> Asian persons. Dermatol Surg.2004; 30(9):1196-200.15. Sherwood KA, Murray S, Kurban, AK et al. Effect <strong>of</strong> wavelengthon cutaneous pigment us<strong>in</strong>g pulsed irradiation. J Invest Dermatol1989; 92:717-20.11
Change language