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Toxicological Evaluation and Limit Values for ... - Miljøstyrelsen

Toxicological Evaluation and Limit Values for ... - Miljøstyrelsen

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9 Quality criteria9.1 Quality criteria in soilNPA limit value of 25 mg/kg has been calculated based on children’singestion of soil. A quality criterion of 25 mg/kg soil is proposed.Quality criteriaQuality criterion: 25 mg/kg soilNPEA limit value of 65 mg/kg has been calculated based on children’singestion of soil. A quality criterion of 65 mg/kg soil is proposed.Quality criteriaQuality criterion: 65 mg/kg soil9.2 Quality criteria in drinking waterThe existing limit value <strong>for</strong> phenols in drinking water of 0.5 µg/l offersadequate protection against adverse health effects induced by NP orNPE.Quality criteriaQuality criterion: 0.5 µg/l.9.3 C-valueNPA limit value of 0.017 mg/m 3 has been calculated based on toxicologicalconsiderations in relation to repeated oral exposure. For substanceshaving acute or subchronic effects, but <strong>for</strong> which activity over a certainperiod of time is necessary be<strong>for</strong>e the harmful effect occurs, the C-valueis set at the limit value.A C-value of 0.02 mg/m 3 <strong>and</strong> placing in Main Group 1 is proposed. MainGroup 1 is justified because of concern <strong>for</strong> the environment due to thepersistence of NP. This proposed C-value also protects against sensoryirritation caused by NP.C-value0.02 mg/m 3 , Main Group 1.NPEA limit value of 0.05 mg/m 3 have been calculated based on toxicologicalconsiderations in relation to repeated oral exposure. For substanceshaving acute or subchronic effects, but <strong>for</strong> which activity over a certainperiod of time is necessary be<strong>for</strong>e the harmful effect occurs, the C-value39

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