INTEGRILIN® (eptifibatide) Injection Clinical Support Slide Lecture ...

INTEGRILIN ® (eptifibatide) Injection:Precautions and Warnings (continued)• In patients undergoing PCI, INTEGRILIN ® is associated withan increase in major and minor bleeding at the site of arterialsheath placement. Special care should be employed tominimize the risk of bleeding among these patients.• If bleeding cannot be controlled with pressure, infusion ofINTEGRILIN ® and concomitant heparin should be stoppedimmediately.• Because INTEGRILIN ® inhibits platelet aggregation, cautionshould be employed when it is used with drugs that affecthemostasis, including thrombolytics, oral anticoagulants,NSAIDs, and dipyridamole.• Use with other parenteral GP IIb-IIIa inhibitors should beavoided.INTEGRILIN ® (eptifibatide) Injection Prescribing Information. 6/06 Schering Corporation.