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National best practice and evidence based guidelines for wound ...

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NatioNal <strong>best</strong> <strong>practice</strong> aNd evideNce <strong>based</strong> guideliNes <strong>for</strong> wouNd maNagemeNt<br />

56<br />

● Ketoacidosis: A subsequent build up of acids (keto bodies) in the blood, resulting in a condition<br />

of acidosis <strong>and</strong> associated with hyperglycaemia.<br />

● Laceration: Produced when a blunt object strikes the skin with sufficient <strong>for</strong>ce to stretch <strong>and</strong> tear<br />

it. A crushing injury ensues <strong>and</strong> the margins of the <strong>wound</strong> may be ragged, abraded <strong>and</strong> bruised.<br />

● Lesion: A broad term referring to abnormalities in tissues, may be visible as tissue injury, sores<br />

or ulcers.<br />

● Maceration: A softening or sogginess of the tissue owing to retention of excessive moisture.<br />

Usually presents as moist red/white <strong>and</strong> wrinkled.<br />

● Macrophage: Blood cells which destroy bacteria <strong>and</strong> devitalised tissue <strong>and</strong> produce a variety of<br />

growth factors.<br />

● Methicillin-Resistant Staphylococcus aureus (MRSA): Staphylococcus aureus bacterium<br />

that is not succeptible to extended-penicillin antibiotic <strong>for</strong>mulas, such as Methicillin, oxacillin<br />

or nafcillin.<br />

● MMP Matrix metalloproteinase: enzymatic compound capable of connective tissue<br />

degradation; classified as collagenases, gelatinases <strong>and</strong> stromelysins.<br />

● MVTR: Moisture vapour transmission rate; measured in units of weight of moisture vapour per<br />

area of material per time period.<br />

● Necrosis: The local death of tissue. This tissue is often black/brown in colour <strong>and</strong> leathery in<br />

texture.<br />

● Neuro-ischaemic: The combination of diabetic neuropathy <strong>and</strong> peripheral arterial disease.<br />

● Neuropathy: Nerve damage leading to numb or sometimes painful feet.<br />

● NPUAP: <strong>National</strong> Pressure Ulcer Advisory Panel.<br />

● Onychauxis: Thickening of the nails.<br />

● Onychocryptosis: Nail de<strong>for</strong>mities such as ingrown toenails.<br />

● Onychogryphosis: De<strong>for</strong>mities of the nails.<br />

● Orthosis: An appliance which controls, corrects or accommodates a structural or functional<br />

abnormality.<br />

● Osteomyelitis: Inflammation of bone <strong>and</strong> marrow usually caused by pathogens that enter the<br />

bone during an injury or surgery.<br />

● Overgranulation: See Hypergranulation.<br />

● Pathogen: Any disease- producing agent or micro-organism.<br />

● Pemphigus: A group of serious diseases of the skin characterises by the appearance of bullae<br />

(blisters) of various sizes on apparently normal skin <strong>and</strong> mucous membrane. It is thought to be an<br />

autoimmune disease <strong>and</strong> occurs in men <strong>and</strong> women in middle <strong>and</strong> late adulthood.<br />

● Pemphigus: An uncommon chronic intra-epidermal blistering disease characterised by thin<br />

walled bullae.<br />

● Perfusion: Blood flow to the skin.<br />

● Perioperative: Literally, around (the time of ) surgery. More specifically, the period of time<br />

extending from when the patient goes into the hospital, clinic, or doctor’s office <strong>for</strong> surgery until<br />

the time the patient is discharged home.<br />

● Peripheral arterial disease (PAD): Disease of mostly small blood vessels in the extremities<br />

(h<strong>and</strong>s <strong>and</strong> feet), as narrowing of arteries.

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