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THE OSTIA VENAE HEPATICAE AND THE RETHROHEPATIC ...

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190<br />

ACQUIRED PROGRESSIVE KINKLING OF <strong>THE</strong> HAIR (APKH)<br />

Sukamas Suwanwalaikorn, Apichati Sivayathorn, Kleophant Thakerngpol<br />

Department of Dermatology and Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University<br />

Key words : Alopecia<br />

Faculty of Medicine Siriraj Hospital<br />

(255)<br />

Background : APKH is a rare disorder of scalp hair characterized by rapid onset of<br />

tightly curl hair shaft in association with an increasingly coarse texture resembling pubic hair. These may<br />

follow by progressive hair loss, which lead to common baldness soon after the event. The main affected<br />

areas are in the frontal-parietal and vertex regions which correspond to those usually involve in androgenetic<br />

alopecia (AGA). It occurs primarily at or soon after puberty and is more common in males. Hormonal<br />

changes may play an important role in pathophysiological events.<br />

Methods and patients : We report 2 cases, which demonstrated the changes in hair<br />

abnormality believed to be characteristic of APKH.<br />

Case I. M.S., 28 year-old woman, complained of progressively hair loss over period of 2<br />

years. She noticed all these abnormalities after childbirth.<br />

Case II C.C., 21 year-old man presented with one year history of hair loss.<br />

Results : Clinical examination revealed a slight increase in telogen count in the affected<br />

area. Light microscope and scanning electron microscope confirmed the presence of alteration in hair<br />

shaft diameter with partial twists. Canalicular grooves were seen on its longitudinal axis, together with<br />

some broadened and flattened sections. Cross section of the hair showed elliptical or heart-shaped appearances.<br />

Blood tests result including sex hormones and copper level were normal.<br />

Conclusion : The differential diagnosis of APKH includes all the syndromes of woolly<br />

hair, whisker hair, uncombable hair syndrome and all woolly hair occurring as a result of external trauma<br />

and drug. This entity may be more common than previously recognized and is probably a prognostic sign<br />

heralding severe AGA.<br />

(Presented at the Annual Meeting of the Dermatological Society of Thailand, Bangkok, Thailand,<br />

4-5 March 1999)

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