THE OSTIA VENAE HEPATICAE AND THE RETHROHEPATIC ...

even in those with hypomagnesemia. In the patients with Mg depletion, 87% had renal Mg loss (base line
24hU Mg>24mg). In the patients with Mg depletion without renal Mg loss, the fractional excretion of Mg
was >7%. There was no correlation between APACHEII score, Mg retention and serum Mg. The two
patients who died from their illness had higher Mg retention than those who survived while their serum
Mg were higher but both were not statistically significant. No complications were observed during the
test. This study demonstrated that Mg depletion is prevalent in critically ill patients and MLT is a useful
tool, even in those with renal Mg loss, for the assessment of Mg status.
A LONG-TERM COMPARISON OF THE EFFECTS ON RENAL FUNCTION
OF BP CONTROL WITH EITHER ATENOLOL (A) OR ENALAPRIL(E) IN
POLYCYSTIC KIDNEY DISEASE (PKD)
(302)
Michael L. Watson 1 , Anne M. Macnicol 1 , J. Borg-Costenzi 2 , K. Vareesanghip 3 , Dominique
Chauveau 4 , Geoff Cohen 1 , M. Elasad 3
1 Medicine, Royal Infirmary, Edinburgh, United Kingdom; 2 Medicine, Royal Infirmary, Manchester,
United Kingdom; 3 Medicine, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom;
4 Nephrology, Necker Hospital, Paris, France.
54 patients with PKD, mild renal impairement and hypertension were randomised to the
two treatment groups (A or E) and followed for 3 years.
BP and renal function (inulin clearance) were similar in each group at randomisation:
(A:147.9/99.0 mmHg, 115.6ml/min/1.73sqm; E 150.7/100.8 mmHg, 113.1ml/min/1.73sqm. Treatment in
each group was titrated to achieve the BP target (sitting diastolic BP