12.07.2015 Views

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

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WG’s: MythThere is considerable evidence that patients with high titersof ANCA are at risk of relapse <strong>and</strong> that ris<strong>in</strong>g titers mayprecede relapseSome patients with persistently high ANCA titers rema<strong>in</strong>free of disease for yearsIt is not clear whether the ANCA <strong>in</strong> these cases differsfrom that detected <strong>in</strong> other patients or whether thesepatients lack some additional stimulus required for a flareJayne D, Gask<strong>in</strong> G, Pusey C, et al: ANCA <strong>and</strong> prediction of relapse <strong>in</strong> systemic vasculitis. Q J Med 88:127-133, 1995

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