12.07.2015 Views

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

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Giant Cell Arteritis: PearlThe study by Hall et al also provided some important<strong>in</strong>formation about the negative predictive value of temporalartery biopsies.With a median follow-up <strong>in</strong>terval of 70 months for the 88patients with negative biopsies (which were bilateral ifbiopsy of the <strong>in</strong>itial side was negative on frozen section),only 8 patients were ultimately diagnosed with GCA despitehav<strong>in</strong>g negative biopsiesThis amounts to a negative predictive value of 91% forbiopsies performed <strong>in</strong> this fashionHall S, Lie J, Kurl<strong>and</strong> L, et al: The therapeutic impact of temporal artery biopsy.Lancet 2:1217-1220,1983

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