12.07.2015 Views

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

Clinical Pearls and Myths in Vasculitis

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Polyarteritis Nodosa: PearlBiopsy of skeletal muscle, a highly vascular tissue,<strong>in</strong>creases the yield of the procedure substantially.Even when there are no symptoms, signs, or laboratoryabnormalities <strong>in</strong>dicative of skeletal muscle <strong>in</strong>volvement (e.g.,abnormal serum creat<strong>in</strong>e k<strong>in</strong>ase levels), a gastrocnemiusbiopsy may demonstrate the pathognomonic f<strong>in</strong>d<strong>in</strong>gs ofvasculitis.

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