Burt, Dave - The Roslin Institute - University of Edinburgh
Burt, Dave - The Roslin Institute - University of Edinburgh
Burt, Dave - The Roslin Institute - University of Edinburgh
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Gene Family Expansion andContraction <strong>of</strong> Adaptive Significance?• CAFE “Computational Analysis <strong>of</strong> gene FamilyEvolution” (Hahn et al, 2007) was used to predict genefamily expansions and contractions <strong>of</strong> putative adaptivevalue• CAFE models gene expansion/contraction as a“birth/death” process with a specific probability• This value may be the same for all lineages or may varyin two or more lineages• <strong>The</strong> likelihood can be calculated and compare differentmodels24