12.07.2015 Views

Role of Mirena in HRT - Nick Panay

Role of Mirena in HRT - Nick Panay

Role of Mirena in HRT - Nick Panay

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Aerodiol, , a unique pharmacok<strong>in</strong>etic pr<strong>of</strong>ile• Aerodiol a new concept <strong>in</strong> <strong>HRT</strong>, pulsed oestrogen therapy.• This pulsed effect ensures effective oestrogenexposure <strong>in</strong> the target tissues• Aerodiol is characterised by an orig<strong>in</strong>alpharmacok<strong>in</strong>etic pr<strong>of</strong>ile differ<strong>in</strong>g from the somewhatflatter, more susta<strong>in</strong>ed k<strong>in</strong>etic pr<strong>of</strong>iles seen withtransdermal and oral therapy.Devissaguet et al. (1999) Eur J Drug Metabol 24, 256-271

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