12.07.2015 Views

Role of Mirena in HRT - Nick Panay

Role of Mirena in HRT - Nick Panay

Role of Mirena in HRT - Nick Panay

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New delivery vehicles for progestogensProgesterone creamo Progestogenic opposition– Wren BG et al 1999 Lancet• E100 v Placebo• No endometrial transformation• Progesterone cream alone– Leonetti et al 1999 Obstet Gynecol• RCT over 1 year <strong>of</strong> progesterone v placebo• Vasomotor benefits; no effect on bone density

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