Role of Mirena in HRT - Nick Panay
Role of Mirena in HRT - Nick Panay
Role of Mirena in HRT - Nick Panay
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<strong>HRT</strong> delivery systems - sk<strong>in</strong>Transdermal sk<strong>in</strong> patch systems• Mechanism <strong>of</strong> action– Passive diffusion– Lipid soluble substances– Lipophilic spaces between kerat<strong>in</strong>sed cells <strong>of</strong> stratum corneum• Types– Reservoir : steroid <strong>in</strong> gel with alcohol as flux enhancer– Matrix : steroid dispersed evenly <strong>in</strong> adhesive matrix asmicronised suspension