Comparative Neuro-Ophthalmology - North Carolina State ...

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Oculo-Pupillary Reflex• Afferent arm = ophthalmic division ofCNV• Efferent arm = parasympathetic divisionof CN III• Sensory stimulation of corneal (sclera)resulting in miosis and ciliary mm.spasm
Axon Reflex• stimulation of ophthalmic division of CN V (cornea,conjunctiva, eyelids)- prodromic axoplasmic flow/transmission- antidromic flow through terminal branches of CNVinnervating iris and ciliary body• release of AcH, prostaglandins, substance P, vasoactivecompounds, other inflammatory mediators• miosis, disruption of blood-aqueous barrier, ocularhypertensionBito, LZ. Species differences in the responses of the eye to irritation andtrauma: a hypothesis of divergence in ocular defense mechanisms, andthe choice of experimental animals for eye research. Exp Eye Res 1984Dec;39(6):807-29
Page 1 and 2: Comparative Neuro-OphthalmologyMich
Page 3: Suggested Reading• Shamir MH, Ofr
Page 6 and 7: AFFERENT ARM OF PLR:• rod/cone ph
Page 9 and 10: • optic nerve fibers convergeat c
Page 11 and 12: LG BodyPTN; R.ColliculusII
Page 13 and 14: Afferent Arm of PLR• pretectal nu
Page 15 and 16: Postganglionic, ParasympatheticCili
Page 17: Ciliary Body Innervation andAccommo
Page 21 and 22: Evaluating Pupillary Light Reflexes
Page 23 and 24: Swinging Flashlight Test• “Posi
Page 25 and 26: Dark Adaptation Test• normal = bo
Page 27 and 28: Retinal Chain, Intraocular RetinalG
Page 29 and 30: Unilateral Optic Tract Lesions• s
Page 31 and 32: • ipsilateral dilated pupil• no
Page 33 and 34: ExternalOphthalmoplegia• motor de
Page 35 and 36: Pharmacologic Localization of Lesio
Page 37 and 38: Pharmacologic Testing withParasympa
Page 39 and 40: Efferent Sympathetic Pathway:1st Or
Page 41 and 42: Efferent Sympathetic Pathway: 3rdOr
Page 43 and 44: Horner’s Syndrome• protrusion o
Page 45 and 46: Horner’s Syndrome in Large Animal
Page 47 and 48: Localization of Pupillary Abnormali
Page 49 and 50: Anisicoria: Unilateral Mydriasis•
Page 51 and 52: Anisicoria: Unilateral Mydriasis•
Page 53 and 54: Localizing Horner’s Syndrome with
Page 55 and 56: Bilateral Miosis• Extensive brain

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