Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
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IH-SR LANGENDORFFISOLATED HEART PERFUSION SYSTEMIH-SR Langendorff: The Basis forAny <strong>Heart</strong> <strong>Perfusion</strong> StudySTARLING RESISTOR• The IH-SR can be purchased as a workingheart-ready upgradeable system by addingour Patented Membrane Flow Resis<strong>to</strong>r insteadof the SCP <strong>Perfusion</strong> Controller• The Starling Resis<strong>to</strong>r allows for a simplemechanical switch between Constant Flowand Constant Pressure <strong>Perfusion</strong>• While pressure remains constant the flowwill vary and will be directly measured by thebuilt-in transit-time ultrasonic aortic flow probePERFUSATE SUPPLY& PERIPHERALEQUIPMENT• Unique Double-Walled GlassReservoir with Aeration Pathway• Roller Pump with FeedbackControl• Thermocircula<strong>to</strong>r• Electrical Stimula<strong>to</strong>r for PacingISOLATED HEART PERFUSION SYSTEMBENEFITS:AORTIC BLOCK• Core of the System• Very Low Flow Resistance• Small Dead Space Volume• Integrated Bubble Trap andShut-Off S<strong>to</strong>pcock• Highly Stable Attachment Point forthe <strong>Heart</strong>, Probes and Electrodes• Solid State Physiological <strong>Perfusion</strong>Circuit for Stable Pressure & FlowControl• Compact Design,Optimized for: Mouse,Rat, Guinea Pig• Constant Pressure orConstant Flow in One Unit• Modular Design <strong>to</strong>Integrate MoreApplications in the Future• Unique Aortic Block and<strong>Heart</strong> Chamber AllowsUnsurpassedPhysiological SimulationPLUGSYS• Modular Amplifier System• Low Noise, Analog Fidelityand Control• Huge Range of MeasurementCapabilities• Grows <strong>to</strong> Fit Your Application• Compact, Space-SavingArrangement• Can Output Signals <strong>to</strong> VirtuallyAny Data Acquisition SystemBASIC MEASUREDPARAMETERS• <strong>Perfusion</strong> Pressure• Coronary Flow• Isovolumetric LVPHEART CHAMBER• Closes Fully for SuperiorTemperature Control• Spacious Enough for a Range ofPhysiological MeasurementProbes and Electrodes• Opens & Swings Completely Ou<strong>to</strong>f the Way for Easy Adjustment of<strong>Heart</strong> and Probes• Removable for easy cleaning• Small Flow Resistanceand Low Dead SpaceVolume for HighlyReproducible andAccurate Results• Low Volume DrugInjection Pathway is Idealfor Compound Screening• A Complete, FlexibleSystem for a Range ofApplications14 email physiology@harvardapparatus.com web www.hugo-sachs.de • www.harvardapparatus.comemail physiology@harvardapparatus.com web www.hugo-sachs.de • www.harvardapparatus.com 15
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