Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
Guide to Isolated Heart Perfusion Systems - Harvard Apparatus
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IH-5 LANGENDORFFISOLATED HEART PERFUSION SYSTEMCONVENIENTACCESS PORTS• Drug Injection Pathway Built Directly inAortic Perfusate Stream• Integrated S<strong>to</strong>pcock Allows SwitchingBetween a Primary and SecondaryPerfusate (such as Cardioplegia Solution)• Secondary Drug Injection Port or ProbePort for inserting Catheter-Type Probes(e.g. Temperature)IH-5 Basic: The PreferredElectrophysiology & SafetyChoice for CardiacPharmacologyAORTIC BLOCK• Core of the System• Low Flow Resistance: Engineered forIncreased Flow up <strong>to</strong> 500 ml/min• Unique Small Volume Aortic Blockwith Built-In Bubble Trap &Windkessel- Reproduces In Situ ElasticProperties of the Aorta- Adjustable Air Volume inWindkessel for OptimalPulsation Dampening• Solid State <strong>Perfusion</strong> TechnologyMimics In Vivo <strong>Perfusion</strong> andPrevents Measurement Artifact• Highly Stable Attachment Point forthe <strong>Heart</strong>, Probes & Electrodes• Unique Proprietary Aortic Cannulae- Multiple Sizes Available(2 – 6 mm OD)- Suture Rings Allow No-Slip<strong>Heart</strong> Mounting- Rugged Stainless Steel –No Fragile GlassISOLATED HEART PERFUSION SYSTEMFEATURES:HEART CHAMBER& PLATFORM• Large Chamber forAccommodating a Range ofPhysiological Probes andElectrodes• Knob Conveniently Raises andLowers Eleva<strong>to</strong>r Platform• Fully Surrounds <strong>Heart</strong> & LowerAortic Block for TemperatureStability• Suitable for <strong>Heart</strong>s from HypertensiveAnimals with <strong>Perfusion</strong> Pressures up<strong>to</strong> 300 mmHg• Compact System, No HighWall-Installed Water Columns• Constant Pressure and Constant Flow<strong>Perfusion</strong> in One Unit• Modular System is FullyUpgradeable/Expandable atany Time• Large 6 L Perfusate ReservoirAccommodates Enough Perfusate forRabbit Langendorff and Working<strong>Heart</strong> Requirements (2 L Available forsmaller species)PLUGSYS• Modular Amplifier System• Low Noise, Analog Fidelityand Control• Compact, Space-SavingArrangement• Output Signals <strong>to</strong> VirtuallyAny Data Acquisition System• Largest Range ofMeasurement Capabilities withOptional Case ExpansionWORKING HEARTREADY• Equip the Langendorff CoreSystem with Direct FlowMeasurement and the StarlingConstant Pressure Control Option<strong>to</strong> Make your System Working<strong>Heart</strong> Ready for Later UpgradeBASIC MEASUREDPARAMETERS• <strong>Perfusion</strong> (Aortic) Pressure• Coronary Flow• Isovolumetric LVPELECTROPHYSIOLOGY& SAFETYPHARMACOLOGY• Single or Multi-Lead ECGAnalysis (up <strong>to</strong> 12)• ECG Mapping• Epicardial Monophasic ActionPotentials (up <strong>to</strong> 8)• Endocardial MonophasicAction Potential24 email physiology@harvardapparatus.com web www.hugo-sachs.de • www.harvardapparatus.comemail physiology@harvardapparatus.com web www.hugo-sachs.de • www.harvardapparatus.com 25
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