EPITAN - Clinuvel Pharmaceuticals

20Prevention of sunburn injuryYear 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023US marketPopulation (m) 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0 290.0% Fitzpatrick types I-II 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00No. Fitzpatrick types I-II (m) 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0 145.0% Fitzpatrick types I-II usingsunprotection products 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30No. Fitzpatrick types I-II usingsunprotection products (m) 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50 43.50% Maximum penetration of Melanotan 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0Total patients treated at peak (m) 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18 2.18% of peak penetration 0.0 0.0 0.0 2.0 20.0 40.0 60.0 80.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 90.0 70.0 30.0 10.0Cost of treatment per patient per year ($) 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0Revenue generated ($m) 0.0 0.0 0.0 8.7 87.0 174.0 261.0 348.0 435.0 435.0 435.0 435.0 435.0 435.0 435.0 391.5 304.5 130.5 43.5EU market (top 5 countries)Population (m) 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0 300.0% Fitzpatrick types I-II 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00No. Fitzpatrick types I-II (m) 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0 150.0% Fitzpatrick types I-II usingsunprotection products 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30No. Fitzpatrick types I-II usingsunprotection products (m) 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00 45.00% Maximum penetration of Melanotan 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0Total patients treated at peak (m) 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25 2.25% of peak penetration 0.0 0.0 0.0 2.0 20.0 40.0 60.0 80.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 90.0 70.0 30.0 10.0Revenue generated ($m) 0.0 0.0 0.0 9.0 90.0 180.0 270.0 360.0 450.0 450.0 450.0 450.0 450.0 450.0 450.0 405.0 315.0 135.0 45.0Australia/New ZealandPopulation (m) 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0 24.0% Fitzpatrick types I-II 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00 50.00No. Fitzpatrick types I-II (m) 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00 12.00% Fitzpatrick types I-II usingsunprotection products 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30 30No. Fitzpatrick types I-II usingsunprotection products (m) 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60 3.60% Maximum penetration of Melanotan 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0Total patients treated at peak (m) 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18 0.18% of peak penetration 0.0 0.0 0.0 2.0 20.0 40.0 60.0 80.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 90.0 70.0 30.0 10.0Cost of treatment per patient per year ($) 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0 200.0Revenue generated ($m) 0.0 0.0 0.0 0.7 7.2 14.4 21.6 28.8 36.0 36.0 36.0 36.0 36.0 36.0 36.0 32.4 25.2 10.8 3.6Total revenues - prevention of sunburn injuryUS $m 0.0 0.0 0.0 8.7 87.0 174.0 261.0 348.0 435.0 435.0 435.0 435.0 435.0 435.0 435.0 391.5 304.5 130.5 43.5EU $m 0.0 0.0 0.0 9.0 90.0 180.0 270.0 360.0 450.0 450.0 450.0 450.0 450.0 450.0 450.0 405.0 315.0 135.0 45.0Aus/NZ $m 0.0 0.0 0.0 0.7 7.2 14.4 21.6 28.8 36.0 36.0 36.0 36.0 36.0 36.0 36.0 32.4 25.2 10.8 3.6Total 0.0 0.0 0.0 18.4 184.2 368.4 552.6 736.8 921.0 921.0 921.0 921.0 921.0 921.0 921.0 828.9 644.7 276.3 92.1Source: T&G researchEPITAN