Antiviral Activity and Phytochemical Analysis of Ailanthus Excelsa ...

JOURNAL OF FOREST PRODUCTS & INDUSTRIES, 2013, 2(3), 30-33 ISSN:2325–4513(PRINT) ISSN 2325 - 453X (ONLINE)33VI. CONCLUSIONAilanthus excelsa bark Chloroform extract can be as a promisingsource as antiviral agent and this is due to the presence of theinteresting bioactive phytoconstituents as quassinoids andalkaloids (canthin-6-one ) and it may be appropriate for furthertherapeutic studies against herpes viruses.Conflict of interestThere is no conflict of interest associated with the authors of thispaper.REFERENCES[1] Clark, A. M. (1996). Natural Products as a Resource for New Drugs.Pharmaceutical Research 13: 1133-1141.[2] Cragg, G. M. and Newman, D. J. (2005). Plants as a source of anticanceragents. Journal of Ethanopharmacology 100: 72-79.[3] Shrimali, M., Jain, D. C., Darokar, M. P., Sharma, R. P. (2001).Antibacterial activity of Ailanthus excelsa (Roxb.). Phytotherapy Research15:165-166.[4] Joshi, B. C., Pandey, A., Sharma, R. P, Khare, A. (2003b). Quassinoidsfrom Ailanthus excelsa Phytochemistry 62: 579-584.[5] Dhanasekaran, S., Suresh, B., Sethuraman, M., Rajan, S. and Dubey, R.,(1993). Antifertility activity of Ailanthus excelsa Linn in female albino rats.Indian Journal of Experimental Biology 31:384-391.[6] Ogura, M., Cordell, G. A., Kinghorn, A. D., Farnsworth, N. R. (1977).Potential anticancer agents VI. Constituents of Ailanthus excelsa(Simaroubaceae). Lioydia 40: 579-584.[7] Asolkar, L. V., Kakkar, K. K., Chakre O. J. (1992) “ Glossary of IndianMedicinal Plants with Active Principles ” , C.S.I.R., New Delhi, Part-I, pp. 34-58.[8] Cordell GA, Ogura M, Farnsworth NR. (1978). Alkaloids constituents ofAilanthus excelsa. Lioydia 41, 166- 168.[9] Said A., Rashed K., Tokuda H., Huefner A.(2012). Antitumor activity ofAilanthus excelsa Roxb. stem bark fractions and of canthin-6-one. IUFSJournal of Biology 71(1): 112-121.[10] Nag A, Matai S. (1994). Ailanthus excelsa Roxb. (Simaroubaceae), apromising source of leaf protein. Journal of Agriculture and Food Chemistry,35: 1115-1117.[11] Khan, S. A, Shamsuddin, K. M. (1980). Glaucarubol from Ailanthusexcelsa. Phytochemistry 19:2484-2485.[12] Joshi, BC., Pendey, A, Chaurasia L., Pal M., Sharma R. P., Khare A.(2003a). Antifungal activity of the stem bark of Ailanthus excelsa.Fitotherpia 74:689-691.[13] Said A, Tundis R, Hawas WU, El-Kousy S, Rashed K, Menichini F,Bonesi M, Huefner A, Monica RL, Menichini F. (2010). In vitro Antioxidantand antiproliferative activities of flavonoids from Ailanthus excelsa (Roxb)(Simaroubaceae) leaves. Z. Naturforsch, 65c, 180-186.[14] Connolly J. D, Overton K. H, Polonsky J. (1970). The chemistry andbiochemistry of the linonoids and quassinoids. In: Reinhold l, Liwashitz Y(eds) Progress in phytochemistry. Wiley, London, pp 385-412.[15] Wolf, H. H, Swinyard E. A, Goodman L. S. (1962). Anticonvulsantproperties of some N-substituted hydanoins. J Phrama Sci 51:74-76.[16] Harbone, J. B. (1973). Phytochemical methods. Chapman & Hall,London, pp.40-107.[17] Farnsworth, N. R (1966). Biological and phytochemical screening ofplants. Journal of Pharmceutical Sciences 55, 225-276.[18] Geissman, T.A. (1962). The Chemistry of flavonoids compounds.Pergamon, London, pp.126-147.[19] Arisawa, M., Hayashi K, Nikaido T, Koike K, Fujita D, Nunomura N,Tanaka, M, Sasaki T. (1997). International J. of Pharmacology 35 (1):6-14.[20] Husing, G. D, Melnick J. L. (1957). Morphologic characteristics ofplaques produced on monkey kidney monolayer cultures by enteric viruses(poliomyelitis, Coxsackie, and echo groups. Journal of Immunology78:128-135.[21] Ren Z, Zhang C. H, Wang L. J, Cui Y. X, Qi R. B, Yang C. R, Zhang Y.J, Wei X.Y, Lu D. X, Wang Y. F. (2010). In vitro anti-viral activity of thetotal alkaloids from Tripterygium hypoglaucum against herpes simplex virustype 1. Virologica sinica 25:107-114.[22] IIkay O, Berrin Ozcelik, Taner K, Bilge S. (2007). Antiviral activity ofalkaloids isolated from Fumaria and Corydalis species. Z. Naturforsch, 62c,19-26.[23] Nugraha, A.S, Keller P.A. (2011). Revealing indigenous Indonesiantraditional medicine: anti-infective agents. Natural Product Communications6 (12):1953-1966.