CV - Institut für Biomedizinische Optik - Universität zu Lübeck
CV - Institut für Biomedizinische Optik - Universität zu Lübeck
CV - Institut für Biomedizinische Optik - Universität zu Lübeck
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CURRICULUM VITAE:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::Dr. rer. nat. Ramtin Rahmanzadeh<strong>Institut</strong> <strong>für</strong> <strong>Biomedizinische</strong> <strong>Optik</strong><strong>Universität</strong> <strong>zu</strong> <strong>Lübeck</strong>Peter-Monnik-Weg 423562 <strong>Lübeck</strong>Email: rahmanzadeh@bmo.uni-luebeck.deWeb: www.bmo.uni-luebeck.deseit 03/2012Arbeitsgruppenleiter der AG Molekulare Photobiologie, <strong>Institut</strong> <strong>für</strong>biomedizinische <strong>Optik</strong> an der <strong>Universität</strong> <strong>zu</strong> <strong>Lübeck</strong>01/2011 – 02/2012 Wissenschaftlicher Mitarbeiter am <strong>Institut</strong> <strong>für</strong> biomedizinische <strong>Optik</strong>an der <strong>Universität</strong> <strong>zu</strong> <strong>Lübeck</strong>05/2008 – 12/2010 Research fellow am Wellman Center for Photomedicine bei Prof. T.Hasan, Massachusetts General Hospital, Harvard Medical School,Boston, MA, USAEntwicklung einer Photodynamischen Therapie gegen Ki-67exprimiernde Zellen (Cancer Research, 2010)01/2007 – 04/2008 Wissenschaftlicher Mitarbeiter am <strong>Institut</strong> <strong>für</strong> biomedizinische <strong>Optik</strong>bei Prof. R. Birngruber und Dr. G. Hüttmann, <strong>Universität</strong> <strong>zu</strong> <strong>Lübeck</strong>Untersuchungen <strong>zu</strong>r Laserbestrahlung von Goldnanopartikeln <strong>zu</strong>rZelleliminierung und ZellmembranpermeabilisierungPROMOTION04/2003 – 12/2006 Wissenschaftlicher Mitarbeiter in der Laborgruppe Tumorbiologieam Leibniz Forschungszentrum Borstel bei Prof. J. Gerdes imRahmen des BMBF-Verbundprojektes „Photonische Techniken <strong>zu</strong>rzellulären Nanochirurgie“Titel: „ Untersuchungen <strong>zu</strong>r Inaktivierung von Zellen und Proteinenmit Hilfe optischer Absorber”AUSBILDUNG07/1999 – 03/2000 Auslandsstudium an der <strong>Universität</strong> Helsinki, Finnland, im Rahmendes Erasmus Austausch-Programms.10/1996 – 11/2002 Diplomstudiengang Biologie an der Rheinischen-Friedrich-Wilhelms-<strong>Universität</strong> Bonn, Abschluss: Diplom Biologe1986 – 1995 Beethoven Gymnasium, BonnAbschluss: Abitur1
BEGUTACHTETE PUBLIKATIONENRudnitzki F, Bever M, Rahmanzadeh R, Brieger K, Endl E, Groll J, Hüttmann G.Bleaching of plasmon-resonance absorption of gold nanorods decreases efficiency of celldestruction. J Biomed Opt. 2012 May;17(5):058003.Rahmanzadeh R, Rai P, Celli J, Rizvi I, Baron-Lühr B, Gerdes J and Hasan T.Ki-67 as a molecular target for therapy in an in vitro 3D model for ovarian cancer. CancerRes. 2010 Nov 15;70(22):9234-42Rai P, Mallidi S, Zheng X, Rahmanzadeh R, Mir Y, Elrington S, Khurshid A, Hasan T.Development and Applications of Photo-triggered Theranostic Agents. Adv Drug Deliv Rev.2010 Sep 19Yao C, Qu X, Liang J, Zhang Z, Yao B, Hüttmann G, Rahmanzadeh RInfluence of Laser Parameters on Nanoparticle-induced Membrane Permeabilization. J.Biomed. Opt. 2009; Sep-Oct;14(5):054034.Yao C, Zhang Z, Rahmanzadeh R, Hüttmann GLaser-based Gene Transfection and Gene Therapy. IEEE Trans Nanobioscience. 2008Jun;7(2):111-9. Review.Qu X, Wang J, Zhang Z, Koop N, Rahmanzadeh R, Hüttmann GImaging of Cancer Cells using Gold Nanoparticels and Fluorescent Dyes by MultiphotonMicroscopy. J Biomed. Opt. 2008 May-Jun;13(3):031217Phillips JR, Fischer E, Baron M, van den Dries N, Facchinelli F, Kutzer M, Rahmanzadeh R,Remus D, Bartels D. Lindernia brevidens: a novel desiccation-tolerant vascular plant,endemic to ancient tropical rainforests. Plant J. 2008 Jun; 54(5):938-48Rahmanzadeh R, Hüttmann G, Gerdes J, Scholzen TChromophore-assisted laser inactivation of the nuclear protein pKi-67 leads to inhibition ofribosomal RNA synthesis. Cell Prolif. 2007 Jun; 40(3):422-30Rahmanzadeh R. Untersuchungen <strong>zu</strong>r Inaktivierung von Zellen und Proteinen mit Hilfeoptischer Absorber. Dissertation. <strong>Lübeck</strong>: University of <strong>Lübeck</strong>, Germany; 2006Yao C, Rahmanzadeh R, Endl E, Zhang Z, Gerdes J, Hüttmann GElevation of plasma membrane permeability by laser irradiation of selectively boundnanoparticles. J. Biomed. Opt. 2005 Nov-Dec; 10(6):064012Rahmanzadeh R, Müller K, Fischer E, Bartels D, Borsch TThe Linderniaceae and Gratiolaceae are further lineages distinct from the Scrophulariaceae(Lamiales). Plant. Biol. (Stuttg). 2005 Jan; 7(1):67-782
NICHT-BEGUTACHTETE PUBLIKATIONEN:Rahmanzadeh R, Rai P, Gerdes J and Hasan T. “Targeted light-inactivation of the Ki-67protein using theranostic liposomes leads to death of proliferating cells.” Proc. SPIE 7576,757602 (2010), DOI:10.1117/12.843850Hasan T, Rai T, Spring B, Zheng X, Abu-Yousif A, Rahmanzadeh R, Verma S.“Photodynamic therapy to treat ovarian cancer”. National Cancer <strong>Institut</strong>e (NCI) Alliance forNanotechnology in Cancer Bulletin, 4:1‐5, 2010.EINGELADENE PRÄSENTATIONEN:Rahmanzadeh R: Protein inactivation with dye and nanoparticle conjugates. German-Russian Laser Symposium, 12.–18. April 2008, <strong>Lübeck</strong>Rahmanzadeh R, Scholzen T, Gerdes J, Hüttmann G: Cell and Protein inactivation withantibody conjugates. <strong>Institut</strong>e of Biomedical Engineering, September 2007, Xi'an JiaotongUniversity, Xi'an, ChinaRahmanzadeh R, Gerdes J, Scholzen T, Hüttmann G: Cell and Protein inactivation withoptical absorbers. European Conference on Biomedical Optics (ECBO), 17.-21. Juni 2007,MünchenREGULÄRE PRÄSENTATIONEN:Rahmanzadeh R, Celli J, Rizvi I, Gerdes J, Hasan T: The proliferation marker pKi-67 asnovel molecular target for PDT. 13th World Congress of the International PhotodynamicAssociation (IPA), 10.-14. Mai, Innsbruck, ÖsterreichRudnitzki F, Bever M, Brieger K, Rahmanzadeh R, Hüttmann G: Modeling of OpticalProperties and Temperature Distribution in and around Gold Nanorods. EuropeanConference on Biomedical Optics (ECBO), 14.-18. Juni 2009, MünchenRahmanzadeh R: Cell and Protein inactivation with optical absorbers. 9th InternationalSymposium on Laser Precision Microfabrication, 16.-20. Juni 2008, Quebec, KanadaBever M, Rahmanzadeh R, Hüttmann, G: Selective protein knockout by laser inducedheating of gold nanoparticles. European Conference on Biomedical Optics (ECBO), 17.-21.Juni 2007, München3
AUSGEWÄHLTE POSTER PRÄSENTATIONEN:Rahmanzadeh R, Rai P, Rizvi I, Celli J, Baron-Lühr B, Gerdes J and Hasan T: Triggeringcancer cell death using light-inactivation of the Ki-67 protein. 101 st Annual Meeting of theAmerican Society for Cancer Research (AACR), 17.-21. April 2010, Washington DC, USARahmanzadeh R, Rai P, Rizvi I, Celli J, Abu-Yousif A, Baron-Lühr B, Gerdes J and Hasan T:The proliferation marker Ki-67 as novel molecular target in cancer therapy. InternationalConference on Molecular Targets and Cancer Therapeutics of the AACR-NCI-EORTC, 15.-19. November 2009, Boston, MA, USARahmanzadeh R, Scholzen T, Endl E, Gerdes J, Hüttmann G: Laser-irradiated goldnanoparticles and chromophore assisted light inactivation (CALI) as tools for selectiveprotein knock out and cell killing. SPIE-Symposium Biomedical Optics, Photonics West, 21.-26. Januar 2006, San Jose, CA, USA4
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