A review of studies examining the relationship between progression ...

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Table 2: Methods used to analyse the relationship between PFS/ TTP and OSReference Data type Relationships analysed Methods used ResultsLouvet 2001 22 Summarydata fromtrialsMedian PFS and median OSfor individual trial armsSpearman ρ correlation coefficientLinear regressionρ =0.481, p
Reference Data type Relationships analysed Methods used ResultsTang 2007 27 Summarydata fromtrialsMedian PFS/TTP and OS, Nonparametric Spearman rank correlationDifferences (Δ) in medianOS, PFS and TTP,PFS and OS risk reductionNonparametric Spearman rank correlationcoefficientLinear regression (through origin) analysisMedian PFS and OS: ρ=0.79 (95% CI, 0.65 to0.87), p
Page 1 and 2: A REVIEW OF STUDIES EXAMINING THE R
Page 3 and 4: EXECUTIVE SUMMARYIntroductionProgre
Page 5 and 6: CONTENTS1. INTRODUCTION ...........
Page 7 and 8: 1. INTRODUCTION1.1. BACKGROUNDProgr
Page 9 and 10: equivalent incremental benefit in O
Page 11: 2. REVIEW METHODS2.1. SEARCH STRATE
Page 14 and 15: Table 1: Characteristics of include
Page 18 and 19: Reference Data type Relationships a
Page 20 and 21: Reference Data type Relationships a
Page 22 and 23: 4.2. METHODS IN STUDIES USING INDIV
Page 24 and 25: 5.1. DEFINITION OF TREATMENT EFFECT
Page 26 and 27: 5.3. OTHER MEASURES OF CORRELATION
Page 28 and 29: The slope parameters in the linear
Page 30 and 31: Table 4: Summary of results by tumo
Page 33 and 34: many of the papers included in this
Page 35 and 36: 8. REFERENCES1. Therasse, P., Arbuc
Page 37 and 38: 25. Hotta, K., Kiura, K., Fujiwara,
Page 39 and 40: APPENDIX 2: SEARCH STRATEGIESThe in
Page 41: 38 26 or 27 or 28 or 29 (1206968)39

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