Animal Research Facilities 2011 - Tradeline, Inc.

Flexible, efficient solutions for
multispecies program fluctuations
Boehringer Ingelheim Vetmedica, Inc.
Kevin Fowler – Associate Director, R&D Operations
The flexibility/operating efficiency/capital budget sweet spot is being
redefined for vivariums tasked with supporting multiple species,
rapidly changing research priorities, and fluctuating space needs.
Kevin Fowler sets out Boehringer-Ingelheim’s demanding criteria for
holding and procedure space that adapts rapidly across expanding
and contracting studies involving mice, rats, pigs, dogs, horses, and
cattle. He examines findings on layouts and adjacencies, holding room
configurations, finishes, decontamination, and cutting edge flexibility
features that include a split indoor/outdoor vivarium. He details plans
for versatile feed and water distribution, waste treatment, and facility
flows for large animals, small animals, and staff.
Decontamination for large animal areas:
lessons learned on VHP versus ClO2 Oregon Health & Science University
Rick Doughty – Associate Director for Administration
Full decontamination of large animal areas is proving to be a big
hurdle for facility operating staff looking to move to either vaporized
hydrogen peroxide (VHP) or chlorine dioxide (ClO ). The technologies
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and methods that work for rodent facilities may not be equally
effective for large animal housing —a complication that has
significant operating cost repercussions. Rick Doughty documents
Oregon Health & Science University’s experience testing and
implementing both VHP and ClO in an array of animal area types,
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sizes, and conditions. He reports on the direction their research is
taking, staff preferences, training requirements, and costs.
Vivarium renovations to meet European
caging standards
Novartis Institutes for BioMedical Research
Carmine Bianco, MBA, CMAR, RLATg – Head, Animal Care Operations
Many organizations are adopting the new European caging standards
for animal housing to enhance animal welfare, standardize operating
procedures between global programs, and safeguard the quality
of biomedical research. The minimum enclosure volumes and
enrichment requirements set out in the ETS-123 guidelines mean that
the old room size, utilities, and capacity planning metrics no longer
apply. Carmine Bianco illustrates the effect of ETS-123 on Novartis’
operating capacity calculations and the renovations under way to
upgrade caging equipment for EU compliance. He identifies emerging
best practices for realigning existing spaces and programs with
multiple regulatory standards.
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Monday; Nov. 7
Attend all of the General Sessions below
Increasing demand for zebrafish: facility
planning and operations
Memorial Sloan-Kettering Cancer Center and the Weill Cornell Medical College
Neil S. Lipman, VMD – Professor and Director, Center of Comparative Medicine and Pathology
Zebrafish continue to grow as an important and exciting animal model
in developmental biology, cancer, genetics, and immunology. The
ability to support this emerging model provides a key recruitment and
retention advantage. Neil Lipman scopes out the science drivers behind
the robust growth of this model system as he profiles space, staffing,
and management considerations as well as the associated challenges
and solutions for each. He details planning and design considerations
in the development of core shared fish facilities at Memorial
Sloan-Kettering Cancer Center and Weill Cornell Medical Center.
New research methods and technologies
for large animal facilities
Department of Homeland Security, Plum Island Animal Disease Center
James Johnson – Director, Office of National Laboratories
Emerging research requirements and large animal handling processes
coming out of the Plum Island Animal Disease Center should factor
heavily in operational planning, design, and equipment decisions
for vivarium upgrades and new construction. Jamie Johnson sets
out the coming science agenda for animal pathogens and what it
means for capacity, flexibility, containment, and technology planning.
He identifies innovative solutions for program limiting and aging
facility infrastructure. He also illustrates lessons learned thus far
from planning the replacement DHS facility, the National Bio and
Agro-Defense Facility (NBAF). He scopes out the Plum Island relocation
strategy designed to ensure research continuity and safety.
High-value shutdowns: key to research
uptime
University of Colorado Denver
Jori K. Leszczynski, DVM, DACLAM – Director, OLAR & University Veterinarian
A costly shutdown can be the best investment for improved research
productivity. Here, see the argument for performing a full vivarium
reboot for decontamination instead of a maintain-while-operational
service model. Jori Leszczynski sets out a process that delivers
maximum value shutdown maintenance packages by reconciling a
detailed menu of maintenance tasks with the diminishing returns
of extended shutdown durations. She examines decisions on
schedule, budget, labor headcount, and strategies for swing space,
decontamination, and recommissioning. She documents surprises
discovered in a vivarium shutdown and restart that have implications
for overall facility management and research productivity.