Genetics: From Genes to Genomes

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Use of a fusion tooverproduce a geneproductFig. 17.18 cCopyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display17-34
The attenuation of gene expression: Fine tuning the trpoperon through termination of transcription• The presence of tryptophan activates arepressor of the trp operon.• trpR gene produces repressor• Corepressor – tryptophan binds to trp repressorallowing it to bind to operator DNA and inhibittranscriptionCopyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display17-35
Page 1 and 2: Powerpoint to accompanyGenetics: Fr
Page 3: Outline of Chapter 17• There are
Page 6 and 7: Fig. 17.2Copyright © The McGraw-Hi
Page 8 and 9: The utilization of lactose by E. co
Page 10 and 11: The Operon Theory• The players•
Page 12 and 13: The Operon Theory• Induction• L
Page 14 and 15: Experimental evidence for repressor
Page 16 and 17: Inducer releases repressor to trigg
Page 18 and 19: Changes in the operator can alsoaff
Page 20 and 21: Three experiments elucidate cis and
Page 22 and 23: ConstitutiveInsert Figure 17.9chere
Page 24 and 25: Some positive regulators increasetr
Page 26 and 27: Many DNA-Binding proteins containa
Page 28: Most regulatory proteins are oligom
Page 31 and 32: Using the lacZ gene as a reporter o
Page 33: Creating acollection oflacZinsertio
Page 37 and 38: Termination of transcription finetu
Page 39 and 40: Global regulatory mechanisms coordi
Page 41 and 42: What enables transcription of σ 32
Page 43 and 44: Microarrays - a tool for uncovering
Page 45 and 46: Regulation of Virulence Genes inV.
Page 47 and 48: • Isolated a gene that regulates
Page 49: Unanswered Questions Remain• Why

Genetics: From Genes to Genomes

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