Genetics: From Genes to Genomes

Summary• E. coli’s heat shock response is controlled byalternative sigma factors that recognize differentpromoter sequences.• Alternative sigma factors bind to RNA polymeraseas temperatures change to start transcription ofheat shock proteins.• The induction of alternative sigma factors thatrecognize different promoter sequences serve asglobal control regulatory mechanisms in E. coliand many other bacteria.Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display17-42