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Toxicological TestingThe CFSAN “Redbook”Minimum Toxicity TestsShort-term tests for genetic toxicityMetabolism & pharmacokineticstudiesShort-term tox tests with rodentsSubchronic tox tests with rodentsSubchronic tox tests with nonrodentsReproduction study w/ teratologyphaseOne-Yr tox tests with non-rodentsCarcinogenicity study with rodentsChronic tox/ carcinogenicity studywith rodentsConcern LevelsI II IIIX X XXX XX XXX XXXX