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Nutritional Risk Assessment• Data from animal models (both dose response andmechanistic information) as well as human clinical data• Need for application of various types of quantitative andstatistical modeling techniques, including Monte Carlomodels for premarket and active and passivepostmarket monitoring and analyses• Other sources of relevant information on safety from thenew fields of genomics, metabolomics, proteomics, andnow, “nutrigenomics,” etc.

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