Ranking Nucleophiles and Leaving Groups, Hammond's Postulate
Ranking Nucleophiles and Leaving Groups, Hammond's Postulate
Ranking Nucleophiles and Leaving Groups, Hammond's Postulate
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What Makes a Good <strong>Leaving</strong> Group?3. Products are stable; S N 2 wouldn’t work much better inreverse.Example:+ +OH is a much better nucleophile than Br ;this reaction would revert if it ever happened.So it doesn’t happen.Steric Hindrance at the S N 2 Reaction CenterInhibits Reaction