APIC MRSA Elimination Guideline

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Guide to the Elimination of Methicillin-Resistant Staphylococcus aureus (MRSA) Transmission in Hospital SettingsAcknowledgmentsThe Association for Professionals in Infection Control and Epidemiology acknowledges the valuablecontributions from the following individuals:Kathleen Meehan Arias, MS, MT, SM, CICKathryn Aureden, MS, MT (ASCP) SI, CICJudene Bartley, MS, MPH, CICLillian Burns, MT, MPH, CICCheryl Creen, RN, MSNTammy Lundstrom, MD, JDShannon Oriola, RN, CIC, COHNMarcia Patrick, RN, MSN, CICKathleen Risa, MSN, CRNP, CICSpecial thanks go out to Kathy Aureden and Marcia Patrick who worked tirelessly to make this Guidecome together. Their tremendous efforts in collecting and collating the information allowed thepublication to come to fruition.ASSOCIATION FOR PROFESSIONALS IN INFECTION CONTROL AND EPIDEMIOLOGY
Guide to the Elimination of Methicillin-Resistant Staphylococcus aureus (MRSA) Transmission in Hospital SettingsGuide OverviewPurposeThe purpose of this document is to provide evidence-based practice guidance for the elimination ofmethicillin-resistant Staphylococcus aureus (MRSA) transmission in hospital settings.Key ConceptsEffective efforts to eliminate MRSA transmission are guided by completion of a comprehensive, facilityspecificrisk assessment which describes current state and characteristics of the MRSA burden for thatfacility or setting. Knowledge obtained from the risk assessment drives the development of interventionsthat result in enhanced compliance with existing facility practices, or in implementation of appropriateadditional interventions as described in this guidance document.BackgroundIt is estimated that more than 70% of hospital-associated infections are caused by organisms exhibitingmultidrug-resistance. These infections contribute to significant patient morbidity and mortality and resultin limited antimicrobial treatment options as compared to infections caused by non-resistant organisms.CDC Campaign to Prevent Antimicrobial Resistance in Healthcare Settingshttp://www.cdc.gov/drugresistance/healthcare/problem.htmDrug-resistant pathogens are a growing threat to all people, especially in healthcare settings:• Each year nearly two million patients in the United States get an infection in a hospital.• Of those patients, about 90,000 die as a result of their infection.• More than 70% of the bacteria that cause hospital-associated infections are resistant to at least one of the drugsmost commonly used to treat them.• Persons infected with drug-resistant organisms are more likely to have longer hospital stays and require treatmentwith second or third-choice drugs that may be less effective, more toxic and/or more expensive.Increasing Prevalence of Multidrug Resistance:For decades, MRSA has been the most commonly identified multidrug-resistant pathogen in Europe,Asia, Africa, the Middle East and the Americas. Increasing incidence of MRSA is a well-documentedhealthcare and community phenomenon of tremendous concern to medical, public health and laycommunities around the world. 2 In the early 1990s, MRSA was reported to account for 20 – 25 % ofASSOCIATION FOR PROFESSIONALS IN INFECTION CONTROL AND EPIDEMIOLOGY
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APIC MRSA Elimination Guideline

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