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16:21:11 Alternatively, there's this vortex device. This16:21:14 is a metal inhaler that does not have the static16:21:16 electric charge. This is likely more expensive16:21:18 than these. I have no practical experiences with16:21:21 this vortex inhaler.16:21:2316:21:28 So we'll take a quick diversion here and talk16:21:30 about atmospheric science, because this is16:21:33 important with metered dose inhalers. Ozone is16:21:35 both friend and foe. We've heard of ozone alert16:21:37 action days in the summertime when there's no16:21:40 wind. Ozone is irritating to our airways when it16:21:45 is here at ground level, but up in the16:21:46 stratosphere, ozone is very important for the16:21:50 health of us and all living creatures on earth.16:21:53 It's earth's natural sunscreen.16:21:5616:21:56 The World Health Organization estimates that if16:21:59 the ozone layer decreased by 10%, annually there16:22:03 would be an increase of 300,000 non‐melanoma16:22:06 cancers and 4500 melanoma cancers per year in the16:22:10 world. If you had just a 1% decrease in the ozone16:22:14 layer, then you'd have an increase of cataracts of16:22:18 0.5%. So the ozone layer filters out the UVB16:22:24 radiation from the sun.16:22:25 1516:22:27 Back in the 1970's, some scientists discovered the
16:22:30 catalytic reaction, which they received a Nobel16:22:33 Prize for in chemistry in 1995. And everyone16:22:38 knows where I'm going with this. This has to do16:22:40 with chlorofluorocarbons, which was the propellant16:22:44 in metered dose inhalers until fairly recently.16:22:47 The way the catalytic reaction works is that16:22:50 sunlight reacts with the chlorofluorocarbon16:22:54 molecule to knock off a chlorine atom. That16:22:57 interacts with ozone, which is 03. That yields an16:23:01 oxygen molecule and chlorine monoxide. That,16:23:05 then, interacts with an oxygen atom to yield16:23:09 another oxygen molecule and freeze up that16:23:11 chlorine to once again destroy another ozone16:23:14 molecule.16:23:1416:23:15 One chlorine atom can destroy 150,000 ozone16:23:20 molecules. And bromine is 45 times as potent as16:23:24 chlorine. So this certainly could be ‐‐ is a16:23:29 real issue, and in fact, studies have been done16:23:32 looking at what's called the ozone hole over the16:23:36 Antarctic. These are depictions of this ozone16:23:40 hole. It's measured in something called Dobson16:23:42 units. Less than 220, which is the more blue and16:23:46 purple area, defines the ozone hole. This is in16:23:49 September of 1980 and here's September of 2008.16:23:5316:23:54 This is due to our activity here on earth with
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Page 3 and 4: 15:50:56 past medical history is si
Page 5 and 6: 15:53:30 About the only time I coul
Page 7 and 8: 15:56:11 pentamidine once a month.
Page 10 and 11: 15:59:55 central distribution of th
Page 12 and 13: 16:02:58 or the physics behind this
Page 14 and 15: 16:05:43 that tells you the manufac
Page 16 and 17: 16:08:14 months of age. Certainly i
Page 18: 16:11:04 medications to the lower a
Page 22 and 23: 16:15:59 delivered about the Omron
Page 24 and 25: 16:18:41 That's about one‐tenth o
Page 28 and 29: 16:23:57 chlorofluorocarbons. Now,
Page 30 and 31: 16:26:3416:26:36 And lastly, we hav
Page 32 and 33: 16:29:07 And after they sifted thro
Page 34 and 35: 16:31:37 polarizing. There are cert
Page 36 and 37: 16:34:2116:34:22 I put another ques
Page 38 and 39: 16:36:52 mathematician, postulated

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