Global plan for insecticide resistance management in malaria vectors

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Part 4Near-term action planGlobal database• The WHO Global Malaria Programme should consult with countries, Regional Offices and partners to identify a reputableinstitution to host the database, to be overseen by WHO on behalf of Member States.• The WHO Global Malaria Programme should ensure the flow of data on insecticide resistance from countries to theinstitution hosting the global database.• The host organization should set up the database and work with WHO to design an input template for countries. WHO wouldmanage data requests from partners in consultation with countries.Funding and IR monitoring• Donor agencies should ensure that insecticide resistance monitoring is an integral part of all vector control programmegrants.Within 1–2 years.Monitoring plan• National malaria control programmes should, after conducting an initial situation analysis, prepare a plan for routinemonitoring of insecticide resistance (see section 2.2).• National malaria control programmes should raise funds (by mobilizing national and external resources) as required tobuild monitoring capacity and procure the necessary equipment.Capacity-building• National malaria control programmes should continue to build expertise in entomology and insecticide resistance;partnerships should be formed with local and regional research institutes.Global database• The WHO Global Malaria Programme, through the WHO Regional Offices, should contact national malaria controlprogrammes, implementing agencies and research institutions to explain the data that are needed and how they are intendedto be used.Funding and IR monitoring• Donor agencies and multilateral organizations should support countries in preparing appropriate monitoring plans for theimplementation of large vector control grants.2 years and beyond.Monitoring plan• National malaria control programmes should implement routine monitoring plans.96GLOBAL PLAN FOR INSECTICIDE RESISTANCE MANAGEMENT IN MALARIA VECTORS (GPIRM)
Global database• Malaria-endemic countries should submit data on insecticide resistance for inclusion in the database.• WHO, at global, regional, and country level should conduct further discussions with countries and with research andacademic institutions as required to encourage submission of data.4.2.3 Pillar III. New toolsWithin 6–12 months.Investment• Partners in innovative vector control should continue to meet to discuss the current pipeline and urgent needs, with a viewto increasing the focus on products with IRM properties.Within 1–2 years and 2 years and beyond.Investment• Partners in innovative vector control should increase their focus on new products for IRM.4.2.4 Pillar IV. KnowledgeWithin 6–12 months.Research and evidence• The WHO Global Malaria Programme should convene a group of experts focusing on knowledge needs in insecticideresistance, after consultation with the Malaria Policy Advisory Committee.• Partners from research institutes and academia with national malaria control programmes should continue currenttrials and studies on insecticide resistance.Within 1–2 years.Research and evidence• The experts should finalize the research agenda and communicate the highest priorities to the malaria community.• Partners in research institutes and academia should apply to donors, with support from experts, to secure funding forthe research priorities.97
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WHO Global Malaria ProgrammeGLOBAL
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Navigating the GPIRMExecutive summa
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ContributorsThe Global Plan for Ins
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Elissa Jensen, United States Presid
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ForewordThe past decade has seen un
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1.3 Potential effectof resistance o
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2.2 Country activitiesPillar I. Pla
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PART 3 TECHNICALRECOMMENDATIONSFOR
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PART 1THE THREAT OFINSECTICIDE RESI
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Attributes of the four classes of i
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1.2 Status ofinsecticideresistance1
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1.2.2 Resistance is widespread and
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Figure 7: Insecticide-resistance me
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The operational impact of resistanc
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Case study 2. Experimental hut tria
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Figure 12: Genetic heritability dri
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Figure 14: kdr West and kdr East mu
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Monitoring of insecticide resistanc
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Figure 15: Impact of insecticide re
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Page 49 and 50: PART 2COLLECTIVE STRATEGYAGAINST IN
Page 51 and 52: Overview of the strategy against in
Page 53 and 54: 2.2.1 Pillar I. Plan and implement
Page 55 and 56: Step 2: Design an IRM strategy.Prin
Page 57 and 58: Figure 20: Recommendations for moni
Page 59 and 60: Examples of regional entomological
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Page 63 and 64: Standardized data format and timely
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Page 69 and 70: The practical issues in implementat
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Page 75 and 76: 2.5.3 Financial cost of monitoring
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Page 80 and 81: Part 3Technical recommendations for
Page 89 and 90: PART 4NEAR-TERMACTION PLAN4.1 Role
Page 91 and 92: • Convene experts to review new s
Page 93 and 94: Figure 32: What should we do over t
Page 95: Technical support to countries• P
Page 99 and 100: Within 1-2 years.Accelerated fundin
Page 101 and 102: 24. Ranson H et al. Pyrethroid resi
Page 103 and 104: First steps in malaria vector contr
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Page 107 and 108: Annex 2 Long-lastinginsecticidal ne
Page 109 and 110: Annex 3 History of insecticideresis
Page 111 and 112: in many countries, will improve und
Page 113 and 114: Annex 5 Example of ‘tippingpoint
Page 115 and 116: Role of other factors.Recent studie
Page 117 and 118: Annex 8 Main hypotheses usedto mode
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Page 121 and 122: Combinations.How do combinations wo
Page 123 and 124: Figure A9.2: Incremental annual cos
Page 125 and 126: Annex 10 Genetic researchagendaBack
Page 127 and 128: Table A11.1: Cost of indoor residua
Page 129 and 130: References.1. United States Preside
Page 132: For more information, please contac
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Global plan for insecticide resistance management in malaria vectors

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