MMI Clinical and Translational Research Scholars Programme ...
MMI Clinical and Translational Research Scholars Programme ...
MMI Clinical and Translational Research Scholars Programme ...
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Dr Joe MeaneyProf John O’LearyProf Yuri VolkovProf John ReynoldsHigh resolution whole body structural imaging for cardiovascular disease <strong>and</strong> cancer; functionalimaging of tumours with high-resolution 3T MRI compared to PET-CT scanning; imaging ofatherosclerosis with high-resolution 3T MRI.Cancer stem cell biology; tumour transcriptomics; miRNA / naturally occurring anti-sensemolecules.Biomedical applications of nanotechnologies; cell adhesion <strong>and</strong> migration in inflammation <strong>and</strong>cancer; intracellular signalling <strong>and</strong> cytoskeletal dynamics; live cell <strong>and</strong> molecular imaging.Upper gastrointestinal cancer surgery: molecular predictors of sensitivity <strong>and</strong> resistance toneoadjuvant chemoradiotherapy in oesophageal adenocarcinoma; gastrointestinal mucosalimmunology; cellular <strong>and</strong> molecular studies in Barrett’s oesophagus.University College CorkPrincipal InvestigatorProf. David KerinsProf. Noel CapliceDr John CryanProf. Timothy DinanDr Liam FanningProf. Gerald Fitzgerald / Dr PaulO’TooleProf. Jonathan HourihaneProf. Edward JohnsProf. Louise KennyProf. Rosemary O’ConnorProf. Gerry O’SullivanProf. Ivan PerryProf. Eamonn QuigleyDr Anne Moore / Dr ConorO’MahonyDr Declan SodenProf Helen Whelton / Dr Cian ÓMathúnaDr Geraldine Boylan Dr DeirdreMurray / Prof Louise KennyDr Deirdre Murray / Dr MaireadKiely<strong>Research</strong> InterestsPlatelet function <strong>and</strong> vascular diseaseStem cells <strong>and</strong> cardiovascular diseaseMolecular basis of stress induced effects on the brainStress biology, neuro gastroenterologyMolecular diversity of Hepatitis C, Human Immunodeficiency Virus <strong>and</strong> Hepatitis B Viruse<strong>and</strong> how this impacts on disease outcomeComponents of the human gut microbiota <strong>and</strong> their contribution to intestinal healthThe effect of antenatal <strong>and</strong> post natal body composition on metabolic status <strong>and</strong> metabolicrisk factors in children aged 2 <strong>and</strong> 5 years oldNeuro-humoral control of the kidney <strong>and</strong> the impact on blood pressure controlUse of metabolomic technology to search <strong>and</strong> validate early pregnancy biomarkers ofadverse pregnancy outcome; Vascular physiology/biology based programme usinga variety of animal models <strong>and</strong> ex vivo human tissue to search <strong>and</strong> characterise noveltherapeutic targets for preeclampsiaUnderst<strong>and</strong>ing <strong>and</strong> overcoming resistance to therapies that target tyrosine kinasepathways in cancerCancer researchMetabolism <strong>and</strong> disease with a focus on CVD <strong>and</strong> Diabetes including biomarkers of lipidmetabolism <strong>and</strong> inflammationHost-microbiota interactions in gastrointestinal disorders.The application of Micro needles in diagnostics, therapeutics <strong>and</strong> vaccinesCancer Gene Therapy for Lung CancerDevelopment of in-situ models for clinical testing of innovations in oral health careproducts. Collaboration with the Microelectronics Applications Integration Group, TyndallNational InstituteValidation of early placental <strong>and</strong> serum biomarkers in neonatal brain injury.Cardio-metabolic phenotyping in toddlers: body composition <strong>and</strong> metabolic profiles at 2years.10
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