i nun,<strong>1861</strong>.] MuGororrhcsa.—In a paper "on the successful treatment of Gonorrhoeaand Gleet without copaiba," by T, W. Cooke ; surgeon to the EoyalFree Hospital, &a, London," the author, in the first or inflammatorystage, uses antiphlogistic and antacid remedies, avoiding saline purgatives,and a<strong>pp</strong>lying cold lotions. Tn the second stage the treatment (andhere comes in what the author lavs claim to as the great modern improvement,)he trusts to injections of chloride of zinc, \ gr. to grs. iii. adounce, with generous diet. Under those means he informs us that feware not cured within a week, and he has only encountered two cases outattacks of some thousands in which the remedies had failed.Asarum Europium a Remedy tor Drunkards.—Dr. Smirnoffstates that he has become convinced, from repeated trials, that theasarum europceum well deserves the reputation it has obtained inRussia of being an excellent remedy for the effects of drinking. Theinfluence of a continuous abuse of alcoholic drinks is first exerted locally,but afterward- dyspepsia is produced ; and the nutrition and functions ofthe entire economy, especially of the central portions of the nervousling interfered with, the blood itself being loaded with aninjurious foreign material, the dyscrasia potat rem is at last completelyestablished.The asarum fulfils various indications, acting beneficiallyon the alimentary canal in those cases in which the digestivepowers are so much at fault. Its aromatic principle confers upon it astomachic power, and regulates the condition of the intestinal discharges,producing vomiting and purging when given in large doses. Its mostbeneficial action, however, is manifested on the defective a<strong>pp</strong>etite, andtfl counteracting the invincible longing for alcohol. The horriblesensations with which the drinker awakes in the morning, and whichcompel him to seek temporary and delusive relief from renewed libations,are much blunted and mitigated by means of a-trong infusionof a>arum and some other nervine e. g. valerian. Its immediateeffect is often to produce vomiting, and sometimes purging ; but thepainful sensations at the epigastrium undergo relief, and the a<strong>pp</strong>etitebecomes invigorated, Persons who have been long habituated to alcoholicdrinks cannot, however, have these suddenly su<strong>pp</strong>ressed with impunity; and in leg the author gives the asarum in brandy, a<strong>pp</strong>lyingat the same time a blister or an issue to the pit of the stomach. Bythis means the normal activity of the stomach b< I and thelonging for alcohol diminished. The author, however, cannot agreewith those who would still allow a small quantity of spirits to habitualdrink when the morbid desire for ir bac <strong>pp</strong>eased. Theeven when it does not succeedin extinguishing the de-ire for alcohol, ah:•the patient ; and it is reinarkab!in which the individualshave been long accustomed to periodical intervals of drunkenness, endingin delirium tremens, how much longer those interval-- will become, and
———828 Miscellaneous. [<strong>October</strong>,how much less likely delirium tremens is to recur. The patients themselvesare sometimes surprised at the comparative impunity with whichthey can continue their drinking. The author prescribes three or fourglasses a day of an infusion made with three ounces of asarum root, oneounce of valerian root, and half an ounce of orange-peel, but he does notstate the quantity of water employed. In cases of drunkenness, anotherformula is composed of decoction of asarum (made by boiling from halfan ounce to one ounce of the root), six ounces; tincture of valerian, twoto three drachms ; Sydenham's laudanum, gtt.xij ; syrup of orange-peel,half an ounce. A tablcspoonful of this is taken every two hours. Hefinds from two to ttve grains of bismuth, taken four times a day, a valuableadjunct. He has also found the following popular Russian remedyof service in cases of drunkenness :—R. Amnion, carb. half an ounce ;aceti vini, lbj ; oxymel scill. half an ounce. Two tablespoonsfuls everytwo hours. Med, Zcit. Rztsslands and PJtarmaccutical Journal."Mortality from Excision of the Knee Joint.—In a memoirread before the New York Academy of Medicine, Dr. Krackowitzer discussesmore particularly the mortality attending excision of the kneejoint,and the objections which have been urged against the operation.He has collected, from various sources, two hundred and thirty-threecases, which give 4a result of sixty-three deaths and twenty subsequentamputations ; the rate of mortality being twenty-seven in a hundred ; or,including the subsequent amputations, the ratio of failures being thirtysixin a hundred. Of the two hundred and thirty-three cases, thirteenoccurred in the practice of American surgeons. Four of the thirteenpatients died, and two were under treatment at the time of the report,with every prospect of recovering a good limb."Times.American MedicalExcision of the Hip-Joint.—In the statistics of resection of the hipjoint collected by Mr. P. 0. Price, mention is made of the operationhaving been done 59 times. Of that number 33 recovered with goodand useful limbs and greatly benefitted constitutions ;11 were partiallysuccessful—i. e., the patients lived for periods varying from three monthsto two years, and then died, more from other causes than from a recurrenceof the disease which demanded interference; 14 deaths resulteddirectly from the operation, and in 1 the result was unknown. A fairconsideration of the question would show the mortality from the operationto be only 14 out of the 59 cases, or about 23 per cent. ProfessorPirrie states in his "Principles and Practice of Surgery," that he wasextremely anxious to obtain accurate statistics of this operation, butfailed to "procure them from some parts of the world where it had beenseveral times performed. So far as he has been able to learn, the opcrationhad been adopted in 70 cases, and death has resulted from it in 25.Sayre, of New York, gives an analysis of 30 cases, of which 20 recoveredand <strong>10</strong> died, 4 of the latter within one week after the operation.Lancet.
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