LES PUBLICATIONS Daniel MARZIN - Institut Pasteur de Lille

LES PUBLICATIONSLABORATORY OF TOXICOLOGYpreviously EA2690, from january 2010member of the "Equipe d'Accueil""Impact de l'environnement chimique sur la santé humaine"Institut Pasteur de LilleUniversité Lille Nord de FranceResponsableDaniel MARZIN00 33 3 20 87 79 752 0 0 9Gaudin J, Le Hegarat L, Nesslany F, Marzin D, Fessard V.In vivo genotoxic potential of microcystin-LR, a cyanobacterial toxin, investigated both by the unscheduled DNAsynthesis (UDS) and the comet assays after intravenous administration.Environ Toxicol, 2009, 24:200-209.Khandoudi N, Porte P, Chtourou S, Nesslany F, Marzin D, Le Curieux F.The presence of arginine may be a source of false positive results in the Ames test.Mutat Res, 2009, 679, 65-71.Manier N., Deram A., Le Curieux F., Marzin D.Comparison between new wild plant Trifolium repens and Vicia faba on their sensitivity in detecting the genotoxicpotential of heavy metal solutions and heavy metal-contaminated soils.Water, Air, & Soil Pollution, 2009, 202:343-352.Nesslany F, Simar-Meintières S, Ficheux H, Marzin D.Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay.Mutat Res, 2009, 678:13-19.Nesslany F, Parent-Massin D, Marzin D.Risk assessment of consumption of methylchavicol and tarragon : The genotoxic potential in vivo and in vitro.Mutat Res, 2010, 696:1-9.Platel A, Nesslany F, Gervais V, Marzin D.Study of oxidative DNA damage in TK6 human lymphoblastoid cells by use of the in vitro micronucleus test:Determination of No-Observed-Effect Levels.Mutat Res, 2009, 678:30-37.2 0 0 8Courty B, Le Curieux F, Belkessam L, Laboudigue A, Marzin D.Mutagenic potency in Salmonella typhimurium of organic extracts of soil samples originating from urban, suburban,agricultural, forest and natural areas.Mutat Res, 2008, 653:1–5.Nesslany. F., Simar-Meintières S., Watzinger M., Talahari I., Marzin D.Nitrilotriacetic acid : an indirect in vitro and in vivo clastogen.Environ Mol Mutagen, 2008, 49:439-452.Vanhaecke L , Derycke L, Le Curieux F, Sofie Lust, Marzin D, Verstraete W. Bracke M.The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9 tetrahydropyrido[3,2:4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells.Toxicology Letters, 2008, 178:61-69.

2 0 0 7Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, ElhajoujiA, Glatt H, Hastwell P, Hayashi M,Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E,Thybaud V, Tice R, van Benthem J, Vanparys P, White P.How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-upanimal tests : Report of an ECVAM Workshop.Mutat Res, 2007, 628 :31-55.Marzin D.Notion of threshold in mutagenesis : implications for mutagenic and carcinogenic risk assessment.Ann Pharm Fr, 2007, 65:404-414.Nesslany F, Zennouche N, Simar-Meintières S, Talahari I, NKili-Mboui EN, Marzin D.In vivo Comet assay on isolated kidney cells to discriminate genotoxic carcinogens from epigenetic carcinogens orcytotoxic compounds.Mutat Res, 2007, 630:28-41.Thybaud V,Aardema M, Clement J, Dearfield K, Galloway S, Hayashi M, Jacobson-Kram D, Kirkland D,MacGregor J, Marzin D, Ohyama W, Schuler M, Suzuki H, E. Zeiger.Strategy for genotoxicity testing : Hazard identification and risk assessment in relation to in vitro testing.Mutat Res, 2007, 627:41-58.P h DAnne PLATELDirecteurs de thèse : Marc Pallardy et Daniel Marzin"Approches Génotoxiques et Transcriptomiques In Vitro pour la Détermination de Seuils de Produits Induisant desLésions Oxydatives à l’ADN"Université de paris XI19 Mars 2010Imed GARGOURIDirecteur de thèse : Daniel Marzin"Evaluation de l'impact sanitaire des expositions professionnelles aux solvants organiques dans l'industrie des colles etdes chaussures de la région de Sfax – Tunisie"Université de Lille 226 Janvier 2009Nicolas MANIERDirecteur de thèse : Frank Le Curieux"Etude d'un nouveau modèle biologique végétal (Trifolium repens) en écotoxicologie, applicable aux sols contaminés parles métaux lourds(ou éléments traces métalliques, aux choix)"Université de Lille 229 Septembre 2008