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Psychological Support and Mgmt of ICU Psychosis

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Special Considerations for Antipsychotic Usein Older Patients• risk <strong>of</strong> EPS, TD• Sensitivity to anticholinergic effects• 80% have ≥1 serious comorbid medical illness• Age-related differences in drug metabolism• Polypharmacy (increasing risk <strong>of</strong> drug-druginteractions)• >20% <strong>of</strong> nursing home residents on 10 or moremeds 1EPS = extrapyramidal symptoms; TD = tardive dyskinesia.1.Bermabei et al. J Gerontol A Biol Sci Med Sci. 1999;54:M25.

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