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Psychological Support and Mgmt of ICU Psychosis

Psychological Support and Mgmt of ICU Psychosis

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Selective Serotonin Reuptake Inhibitors• Highly effective <strong>and</strong> well tolerated treatments fordepression following TBI 1-8• Present literature is strongest for sertraline 1,3• Treatment with fluoxetine produced significant side effects in>50% <strong>of</strong> patients 5• Anticholinergic effects <strong>of</strong> paroxetine may be problematic 9-10• Effective treatment associated with improvement incognition, other postconcussive symptoms, <strong>and</strong> patientperception <strong>of</strong> severity <strong>of</strong> cognitive impairment 31.Fann, et al. 2000;2.Kant, et al. 1998;3.Fann, et al. 2001;4.Perino, et al. 2001;5.Cassidy. 1989;6.Bessette <strong>and</strong>Peterson. 1992;7.Wroblewski,et al.1992;8.Breen, et al. 1997;9.Fujishiro, et al. 2002;10.Schmitt, et al. 2001.

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