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Practice Parameter and Literature Review of the Usefulness of ...

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<strong>Practice</strong> <strong>Parameter</strong>: Carpal Tunnel SyndromeTable 10. Median Motor Nerve F-Wave Studies in CTS.Author Kuntzer 140Year 1994Number <strong>of</strong> NormalH<strong>and</strong>s (subjects)70 (70)*Normal Subject’s Age:Mean (range)43 (25 to 70)Number <strong>of</strong> CTS H<strong>and</strong>s(patients)100 (100)*CTS Subjects Age:Mean (range)51 (26 to 85)Stimulation SiteWristRecording SiteAPBMinimum H<strong>and</strong>Temperature32°CF-Wave <strong>Parameter</strong> Persistence Chronodispersion Minimal latencyMinimal ulnarmedianF-wavelatency differenceMean durationMean amplitudeMeanamplituderatio†Normal ± SD 92.8 ± 9.2% 1.42 ± 0.37 ms 27.6 ± 2.1 ms 0.59 ± 0.91 ms 10.67 ± 1.62 ms 0.297 ± 0.124 mV 2.97 ± 1.21Criteria for AbnormalValueMean – 2 SD Mean + 2 SD Formula + 2 SD‡ Mean + 2 SD Mean + 2 SD Mean + 2 SD Mean + 2 SDAbnormal Value 2.2 ms SD = 1.4 72.4 >14 ms >0.545 mV >5.39Specificity <strong>of</strong> AbnormalValue91% (actual) 80% (actual) 86% (actual) 90% (actual) 10% (actual) 10% (actual) 70% (actual)Sensitivity <strong>of</strong> AbnormalValue35% 69% 16% 48% 2% 2% 15%* For each reference subject, only 1 h<strong>and</strong> was tested; for each CTS patient, only <strong>the</strong> most symptomatic h<strong>and</strong> was tested.† Mean F-wave amplitude as a percentage <strong>of</strong> <strong>the</strong> median CMAP.‡ Formula: minimum F-wave latency (ms) equals 0.12 × height (cm) + 6.8.Specificity equals <strong>the</strong> percentage <strong>of</strong> reference subjects’ h<strong>and</strong>s with normal results <strong>and</strong> was ei<strong>the</strong>r “actual” based on analysis <strong>of</strong> <strong>the</strong> test data from <strong>the</strong> reference population or an “estimate” basedon <strong>the</strong> statistical distribution <strong>of</strong> test data from <strong>the</strong> reference population.Sensitivity equals <strong>the</strong> percentage <strong>of</strong> CTS patients’ h<strong>and</strong>s with abnormal results calculated from <strong>the</strong> test data on <strong>the</strong> CTS population.CTS = Carpal Tunnel Syndrome SD = St<strong>and</strong>ard Deviation APB = Abductor Pollicis Brevis CMAP = Compound Muscle Action PotentialS940 CTS <strong>Literature</strong> <strong>Review</strong>© 2002 American Association <strong>of</strong> Electrodiagnostic Medicine

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