SREE CHITHRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES TECHNOLOGY

During the study, 4 patients (15.4%) in Azt !,TfOup had sore throat und fever.Lymphadenopathy was seen in two of them. All 4 patients who had sore throat hadpositive throat culture for GAS and elevated ASO indicating GAS infection of throat.None did confirm the criteria for diagnosis of rheumatic fever reactivation.The following is the summary of those who had recurrence of GAS infection:A I: had GAS throat infection while into 3 months of the study .He presented with fever,sore throat and cervical lymph adenopathy .He is a 24 year old man doing agriculturerelated work, belonging to low middle class family. He is in NSR and has mild MR ashis cardiac lesion. He was given curative treatment and in 10 days his throat culture wasnegative. His cardiac status remained same. He was continued on weekly Az.t with nofurther recurrence./\2: had recurrence of GAS sore throat within 3 months of study. He is a J I yr oldmumwl laborer, presented with fever and sore throat. This patient has had PTMC forsevere MS I year back and is in sinus rhythm. He has class I-II symptoms.AJ: is a 42 year old medical nurse, had sore throat and fever with cervicalLymphadenopathy within one month of starting the study drug. She bas mild M R ascardiac lesion. Patient is in NSR./\4: is a clerk ,37 year old lady having mild MS and MR as cardiac lesions with class 1-11symptoms, presented with fever and sore throat within 2 months of study. she is in sinusrhythm and her curdiac status remained same.All patients who had sore throat reported within 3 days of onsets1ncr they wereinstructed to do so. Sledge hammer therapy was instituted as per WHO recommendation.15